rosiglitazone/metformin-oral (cont.)
PRECAUTIONS: This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: kidney disease, liver disease, conditions that may cause a low oxygen blood level or poor circulation (e.g., severe congestive heart failure, recent heart attack, recent stroke), lack of body fluids (dehydration), serious infection, metabolic acidosis (e.g., diabetic ketoacidosis), Type I diabetes (insulin-dependent diabetes). Before using this medication, tell your doctor or pharmacist your medical history, especially of: severe breathing problems (e.g., obstructive lung disease, severe asthma), blood problems (e.g., anemia, vitamin B-12 deficiency), swelling (edema), fertility problems (e.g., ovulation problems), high cholesterol, scheduled upcoming surgery, alcohol use, any allergies. Limit alcohol while using this medication. During times of stress, such as fever, infection, injury or surgery, it may be more difficult to control your blood sugar. Consult your doctor, as a change in your medication may be required. This medication can cause changes in the menstrual cycle (promote ovulation) in women with certain fertility problems, increasing the risk of becoming pregnant. Consult your doctor or pharmacist about the use of reliable birth control while using this medication. Caution is advised when using this drug in the elderly because they may be more sensitive its effects. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known whether this drug passes into breast milk. Breast-feeding is not recommended while using this drug.
DRUG INTERACTIONS: This drug should not be used with the following medication because very serious interactions may occur: insulin. If you are currently using insulin, tell your doctor or pharmacist before starting rosiglitazone/metformin. Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription products you may use, especially of: beta-blockers (e.g., propranolol), birth control pills, calcium channel blockers (e.g., nifedipine), cimetidine, corticosteroids (e.g., prednisone), decongestants, other diabetes drugs (e.g., glyburide, acarbose), estrogens, fenugreek, ginseng, isoniazid, niacin, phenothiazines (e.g., chlorpromazine), phenytoin, thyroid drugs, "water pills" (diuretics such as hydrochlorothiazide, furosemide). If you are scheduled to undergo any x-ray or scanning procedure using injectable iodinated contrast material, be sure to inform your doctor that you are taking this medication. You will need to temporarily stop this medication around the time of your procedure. Consult your doctor for further instructions. Do not start or stop any medicine without doctor or pharmacist approval.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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