SIDE EFFECTS: The most common side effects include
Taking Avandamet with food may help lessen some of these side effects. Other commonly reported side effects include
Rare but serious side effects include new or
- worsening heart failure,
- heart attack,
- edema or swelling (water retention),
- weight gain,
- liver problems,
- macula edema (a diabetic eye disease with swelling in the back of the eye),
- bone fractures,
- low red blood cell count,
- low blood glucose (hypoglycemia), and
- ovulation (increasing the chance of pregnancy).
Metformin can cause a rare but serious condition known as lactic acidosis, a build-up of acid in the blood. Lactic acidosis can cause death and requires immediate treatment. Symptoms of lactic acidosis include
- unusual muscle pain,
- pain in the stomach,
- difficulty breathing,
- dizziness, and
- slow or irregular heartbeat.
Patients suspected of have signs or symptoms of lactic acidosis must seek emergency medical help.
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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