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- What is rosiglitazone, and how does it work (mechanism of action)?
- What brand names are available for rosiglitazone?
- Is rosiglitazone available as a generic drug?
- Do I need a prescription for rosiglitazone?
- What are the side effects of rosiglitazone?
- What is the dosage for rosiglitazone?
- Which drugs or supplements interact with rosiglitazone?
- Is rosiglitazone safe to take if I'm pregnant or breastfeeding?
- What else should I know about rosiglitazone?
What is the dosage for rosiglitazone?
Rosiglitazone may be taken once or twice daily, with or without meals. Daily doses range from 4 to 8 mg either with or without other antidiabetic medications. There is no additional benefit for doses greater than 8 mg per day.
Which drugs or supplements interact with rosiglitazone?
Rifampin decreases concentrations in the blood of rosiglitazone by increasing its breakdown in the liver. Therefore, use of rifampin may decrease the effectiveness of rosiglitazone.
Rosiglitazone should not be combined with nitrates (for example, isosorbide dinitrate [Isordil Titradose, Dilatrate-SR, Isochron]). In clinical trials, the risk of chest pain and heart attacks was greater in individuals on nitrate therapy.
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Need help identifying pills and medications?
Use the pill identifier tool on RxList.