rosiglitazone, Avandia (cont.)

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PRESCRIBED FOR: Rosiglitazone, combined with diet and exercise is used for treating type 2 diabetes in patients who have not responded to other diabetic medications and cannot take pioglitazone (Actos). Rosiglitazone may be used alone or in combination with other types of antidiabetic drugs such as metformin (Glucophage) or sulfonylureas. Since it requires that individuals produce some insulin to be effective, rosiglitazone is not recommended for use in type I diabetes where the amount of insulin is very low or absent.

SIDE EFFECTS AND PRECAUTIONS: The most common side effects seen with rosiglitazone alone or in combination with metformin are:

Rosiglitazone has been shown to cause mild to moderate accumulation of fluid (edema) and can lead to heart failure. Patients who already have heart failure may develop worsening symptoms with rosiglitazone. Therefore, rosiglitazone should not be used by patients with heart failure. Rosiglitazone also has been associated with an increased risk of chest pain and heart attacks. The risk of heart attacks may be greater in those with established heart disease and taking nitrates or individuals receiving insulin.

Medically Reviewed by a Doctor on 12/18/2014

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