Acetylcholine: A key chemical in neurons (nerve cells) that acts as a neurotransmitter and carries information across the synaptic cleft, the space between two nerve cells. Abbreviated ACh.
Acetylcholinesterase: An enzyme that breaks down the neurotransmitteracetylcholine at the synaptic cleft (the space between two nerve cells) so the next nerve impulse can be transmitted across the synaptic gap. Pesticides of the organophosphate and carbamate types act to paralyze and kill insects by inhibiting their acetylcholinesterase. Abbreviated AChE.
Alzheimer's disease: A progressive neurologic disease of the brain that leads to the irreversible loss of neurons and dementia. The clinical hallmarks of Alzheimer's disease are progressive impairment in memory, judgment, decision making, orientation to physical surroundings, and language. A working diagnosis of Alzheimer disease is usually made on the basis of the neurologic examination. A definitive diagnosis can be made only at autopsy. On a cellular level, Alzheimer's disease is characterized by unusual helical protein filaments in nerve cells (neurons) of the brain. These odd twisted filaments are called neurofibrillary tangles. On a functional level, there is degeneration of the cortical regions, especially the frontal and temporal lobes, of the brain. See the entire definition of Alzheimer's disease
Anticholinergic: The action of certain medications that inhibit the transmission of parasympathetic nerve impulses and thereby reduce spasms of smooth muscle (such as that, for example, in the bladder).
Atropine: A drug obtained from belladonna that is administered via injection, eye drops, or in oral form to relax muscles by inhibiting nerve responses. Used to dilate the pupils and as an antispasmodic. See the entire definition of Atropine
Brain: That part of the central nervous system that is located within the cranium (skull). The brain functions as the primary receiver, organizer and distributor of information for the body. It has two (right and left) halves called "hemispheres."
Dementia: Significant loss of intellectual abilities such as memory capacity, severe enough to interfere with social or occupational functioning. See the entire definition of Dementia
Dizziness: Painless head discomfort with many possible causes including disturbances of vision, the brain, balance (vestibular) system of the inner ear, and gastrointestinal system. Dizziness is a medically indistinct term which laypersons use to describe a variety of conditions ranging from lightheadedness, unsteadiness to vertigo. See the entire definition of Dizziness
Dummy: In science experiments, a substance without any active ingredient, a placebo. In the UK, a pacifier: an artificial nipple, usually made of plastic, upon which an infant can suck to gain some solace and quiet down. See the entire definition of Dummy
Enzyme: A protein (or protein-based molecule) that speeds up a chemical reaction in a living organism. An enzyme acts as catalyst for specific chemical reactions, converting a specific set of reactants (called substrates) into specific products. Without enzymes, life as we know it would not exist. See the entire definition of Enzyme
FDA: The Food and Drug Administration, an agency within the U.S. Public Health Service, which is a part of the Department of Health and Human Services. See the entire definition of FDA
Fetus: The unborn offspring from the end of the 8th week after conception (when the major structures have formed) until birth. Up until the eighth week, the developing offspring is called an embryo.
Gastrointestinal: Adjective referring collectively to the stomach and small and large intestines. See the entire definition of Gastrointestinal
Generic:1. The chemical name of a drug. 2. A term referring to the chemical makeup of a drug rather than to the advertised brand name under which the drug may be sold. 3.A term referring to any drug marketed under its chemical name without advertising.
Memory:1. The ability to recover information about past events or knowledge. 2. The process of recovering information about past events or knowledge. 3. Cognitive reconstruction. The brain engages in a remarkable reshuffling process in an attempt to extract what is general and what is particular about each passing moment. See the entire definition of Memory
Nerve: A bundle of fibers that uses chemical and electrical signals to transmit sensory and motor information from one body part to another. See: Nervous system.
Nursing: 1) Profession concerned with the provision of services essential to the maintenance and restoration of health by attending the needs of sick persons. 2) Feeding a infant at the breast.
Offspring: The offspring are strictly speaking the progeny, or young, born to a person. See the entire definition of Offspring
Placebo: A "sugar pill" or any dummy medication or treatment. See the entire definition of Placebo
Pregnancy: The state of carrying a developing embryo or fetus within the female body. This condition can be indicated by positive results on an over-the-counter urine test, and confirmed through a blood test, ultrasound, detection of fetal heartbeat, or an X-ray. Pregnancy lasts for about nine months, measured from the date of the woman's last menstrual period (LMP). It is conventionally divided into three trimesters, each roughly three months long. See the entire definition of Pregnancy
Pregnant: The state of carrying a developing fetus within the body. See the entire definition of Pregnant
Prescription: A physician's order for the preparation and administration of a drug or device for a patient. A prescription has several parts. They include the superscription or heading with the symbol "R" or "Rx", which stands for the word recipe (meaning, in Latin, to take); the inscription, which contains the names and quantities of the ingredients; the subscription or directions for compounding the drug; and the signature which is often preceded by the sign "s" standing for signa (Latin for mark), giving the directions to be marked on the container.
Stomach:1. The sac-shaped digestive organ that is located in the upper abdomen, under the ribs. The upper part of the stomach connects to the esophagus, and the lower part leads into the small intestine. See the entire definition of Stomach
Vomit: Matter from the stomach that has come up into and may be ejected beyond the mouth, due to the act of vomiting. See the entire definition of Vomit
Parkinson's disease is a slowly progressive neurologic disease characterized by a fixed inexpressive face, a tremor at rest, slowing of voluntary movements, a gait with short accelerating steps, peculiar posture and muscle weakness, caused by degeneration of an area of the brain called the basal ganglia, and by low production of the neurotransmitter dopamine. Most patients are over 50, but at least 10 percent are under 40.
Parkinson's disease is the second most common neurodegenerative disorder and
the most common movement disorder. It is characterized by progressive loss of
muscle control, which leads to trembling of the limbs and head while at rest,
stiffness, slowness, and impaired balance. As symptoms worsen, it may become
difficult to walk, talk, and complete simple tasks.
The progression of Parkinson's disease and the degree of impairment vary from
individual to individual. Many people with Parkinson's disease live long
productive lives, whereas others become disabled much more quickly. Premature
death is usually due to complications such as falling-related injuries or
pneumonia.
In the United States, about 1 million people are affected by Parkinson's
disease and worldwide about 5 million. Most individuals who develop Parkinson's
disease are 60 years of age or older. Parkinson's disease occurs in
approximately 1% of i...
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