SIDE EFFECTS: The most commonly-noted side effects associated with risperidone are:
- abdominal pain,
- fever, and
Another important side effect which may also occur include extrapyramidal effects (sudden, often jerky, involuntary motions of the head, neck, arms, body, or eyes) also occur. Risperidone may cause a condition called orthostatic hypotension during the early phase of treatment (the first week or two). Patients who develop orthostatic hypotension have a drop in their blood pressure when they rise from a lying position and may become dizzy or even lose consciousness.
Studies involving risperidone suggest an increased risk of hyperglycemia-related adverse reactions as seen in people with diabetes. Although there is no clear link between risperidone and diabetes, patients should be tested during treatment for elevated blood sugars. Additionally, persons with risk factors for diabetes, including obesity or a family history of diabetes, should have their fasting levels of blood sugar tested before starting treatment and periodically throughout treatment to detect the onset of diabetes. Any patient developing symptoms that suggest diabetes during treatment should be tested for diabetes.
GENERIC AVAILABLE: Yes, risperidone. No, Risperdal Consta
- Tablets: 0.25, 0.5, 1, 2, 3, and 4 mg.
- Oral solution: 1 mg/mL.
- Orally disintegrating tablets: 0.25, 0.5, 1, 2, 3, and 4 mg.
- Powder for injection: 12.5, 25, 37.5, and 50 mg.
STORAGE: Tablets should be kept at room temperature, 15 C to 25 C (59 F to 77 F).
DOSING: Risperidone can be administered once or twice daily. Initial oral dosing for treating schizophrenia is generally 2 mg/day. Dose increases can occur in increments of 1-2 mg/day, as tolerated, to a recommended dose of 4-8 mg/day. In children older than 13 years of age, risperidone should be initiated at 0.5 mg once daily, and can be increased in increments of 0.5 or 1 mg/day, as tolerated, to a recommended dose of 2.5 mg/day. Risperidone can be given with or without meals.
The recommended dose of Risperdal Consta is 12.5 to 25 mg injected into the deltoid or gluteal muscle every two weeks. Dosage should not be adjusted more frequently than every 4 weeks. Patients who have never received risperidone are started on oral risperidone in order to evaluate tolerability. Patients then may be transitioned to Risperdal Consta if oral risperidone is tolerated.
Bipolar mania is treated with oral doses of 2-3 mg/day initially. Dose may be increased by 1 mg/day at every 24 hours up to a dose of 6 mg/day. The dose of Risperdal Consta for bipolar mania is 12.5 to 25 mg injected into the deltoid or gluteal muscle every two weeks. Dosage should not be adjusted more frequently than every 4 weeks.
Quick GuideSchizophrenia Pictures Slideshow: Types, Causes, Symptoms, and Treatment
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