risedronate (Actonel, Actonel with Calcium, Atelvia)

  • Medical Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

What is the dosage for risedronate?

  • For post menopausal osteoporosis, 5 mg of risedronate is taken once daily, 35 mg is taken weekly or 150 mg is taken monthly.
  • For Osteoporosis in men is treated with 35 mg weekly.
  • For Paget's disease is treated with 30 mg daily for two months, and steroid-induced osteoporosis is treated with 5 mg daily.
  • Risedronate should be taken with 6 to 8 ounces of plain water.
  • Because food interferes with the absorption of risedronate, it should be taken first thing in the morning before anything is eaten or liquids consumed.
  • Also, no food or drink should be taken for at least 30 minutes after taking risedronate.
  • To avoid pills sticking and irritating the throat or esophagus, persons should not lie down for at least 30 minutes after taking risedronate.
  • Also, it should not be taken at the same time as iron supplements, vitamins with minerals, or antacids containing calcium, magnesium, or aluminum which reduce the absorption of risedronate.

Which drugs or supplements interact with risedronate?

  • Food, calcium, antacids, and medications containing iron, magnesium, or aluminum reduce the absorption of risedronate, resulting in loss of effectiveness. Thus, it should be taken with plain water only.
Medically Reviewed by a Doctor on 8/5/2016

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