risedronate (Actonel, Actonel with Calcium, Atelvia)

  • Medical Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

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PREPARATIONS:

  • Tablets: 5, 30, 35, and 150 mg.
  • Tablets (Delayed release): 35 mg

DRUG INTERACTIONS:

  • Food, calcium, antacids, and medications containing iron, magnesium, or aluminum reduce the absorption of risedronate, resulting in loss of effectiveness. Thus, it should be taken with plain water only.

PREGNANCY:

  • The safety and effectiveness of risedronate has not been established in pregnant women. Physicians must therefore weigh the potential benefits and unknown risks carefully.
  • The safety of risedronate for the infant has not been established in women who breastfeeding.

STORAGE: Tablets should be stored at room temperature, 15 C - 30 C (59 F - 86 F).

DOSAGE:

  • For post menopausal osteoporosis, 5 mg of risedronate is taken once daily, 35 mg is taken weekly or 150 mg is taken monthly.
  • For Osteoporosis in men is treated with 35 mg weekly.
  • For Paget's disease is treated with 30 mg daily for two months, and steroid-induced osteoporosis is treated with 5 mg daily.
  • Risedronate should be taken with 6 to 8 ounces of plain water.
  • Because food interferes with the absorption of risedronate, it should be taken first thing in the morning before anything is eaten or liquids consumed.
  • Also, no food or drink should be taken for at least 30 minutes after taking risedronate.
  • To avoid pills sticking and irritating the throat or esophagus, persons should not lie down for at least 30 minutes after taking risedronate.
  • Also, it should not be taken at the same time as iron supplements, vitamins with minerals, or antacids containing calcium, magnesium, or aluminum which reduce the absorption of risedronate.
Medically Reviewed by a Doctor on 8/5/2016

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