risedronate, Actonel, Atelvia

  • Medical Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

View the Osteoporosis Slideshow Pictures

SIDE EFFECTS: The most common side effects of risedronate are

Severe irritation of the esophagus (for example, esophagitis, esophageal ulcers, esophageal erosions) can occur. This occurs more often when patients do not drink enough water with risedronate, or do not wait 30 minutes before lying down. Rarely, patients may experience jaw problems (osteonecrosis of the jaw) associated with delayed healing and infection after tooth extraction.

GENERIC AVAILABLE: Yes

PRESCRIPTION: Yes

PREPARATIONS: Tablets: 5, 30, 35, and 150 mg. Tablets (Delayed release): 35 mg

STORAGE: Tablets should be stored at room temperature, 15 C - 30 C (59 F - 86 F).

DOSING:

  • For post menopausal osteoporosis, 5 mg of risedronate is taken once daily, 35 mg is taken weekly or 150 mg is taken monthly.
  • Osteoporosis in men is treated with 35 mg weekly.
  • Paget's disease is treated with 30 mg daily for two months, and steroid-induced osteoporosis is treated with 5 mg daily.

Risedronate should be taken with 6 to 8 ounces of plain water. Because food interferes with the absorption of risedronate, it should be taken first thing in the morning before anything is eaten or liquids consumed. Also, no food or drink should be taken for at least 30 minutes after taking risedronate. To avoid pills sticking and irritating the throat or esophagus, persons should not lie down for at least 30 minutes after taking risedronate. It also should not be taken at the same time as iron supplements, vitamins with minerals, or antacids containing calcium, magnesium, or aluminum which reduce the absorption of risedronate.

Medically Reviewed by a Doctor on 10/9/2015

Quick GuideOsteoporosis Pictures Slideshow: Are Your Bones at Risk?

Osteoporosis Pictures Slideshow: Are Your Bones at Risk?
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