risedronate, Actonel, Atelvia

  • Medical Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

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GENERIC NAME: risedronate

BRAND NAME: Actonel, Atelvia

DRUG CLASS AND MECHANISM: Risedronate is in a class of drugs called bisphosphonates used for the treatment of Paget's disease of bone (in which the formation of bone is abnormal) and in persons with osteoporosis (in which the density and strength of bones are reduced). Other biphosphonates include the drugs alendronate (Fosamax), ibandronate (Boniva), pamidronate (Aredia), tiludronate (Skelid), and etidronate (Didronel). Bone is continually being formed and dissolved. New bone is laid down by cells called osteoblasts while old bone is removed by cells called osteoclasts. Bisphosphonates strengthen bone by inhibiting bone removal (resorption) by osteoclasts. By slowing down the rate at which bone is dissolved, risedronate increases the amount of bone. Risedronate is more potent in blocking the dissolution of bone than etidronate and alendronate. The FDA approved risedronate for the treatment of Paget's disease in 1998 and for the prevention and treatment of osteoporosis in 1999.

PRESCRIBED FOR: Risedronate is used for the treatment of Paget's disease of bone (osteitis deformans), treatment and prevention of postmenopausal osteoporosis in women, and treatment of osteoporosis in men. It also is used to prevent and treat osteoporosis caused by steroid medications (glucocorticoid-induced osteoporosis).

Medically Reviewed by a Doctor on 10/9/2015

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Osteoporosis Pictures Slideshow: Are Your Bones at Risk?
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