rimantadine, Flumadine (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

DRUG INTERACTIONS: Rimantadine may reduce the effectiveness of influenza virus vaccine. It is recommended that rimantadine not be given 48 hours prior to and 14 days after administering the influenza virus vaccine. Rimantadine may interact with monoamine oxidase inhibitors (MAOIs), for example, isocarboxazid (Marplan), phenelzine (Nardil), tranylcypromine (Parnate), and procarbazine (Matulane), and cause the blood pressure to drop suddenly.

PREGNANCY: There are no well-controlled studies of rimantadine in pregnant women and, therefore, rimantadine is not recommended during pregnancy. Other drugs including oseltamivir (Tamiflu) and zanamivir (Relenza) are recommended for the prevention and treatment of influenza A virus illness in pregnant women.

NURSING MOTHERS: It is not recommended that mothers who are breastfeeding use rimantadine due to possible risks of adverse effects in infants.

SIDE EFFECTS: The most common side effects of rimantadine are nausea, vomiting, sleep disturbances, lack of concentration, dizziness and loss of appetite.

Reference: FDA Prescribing Information

Medically Reviewed by a Doctor on 2/21/2014

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