rifampin - oral, Rifadin, Rimactane (cont.)
PRECAUTIONS: Before taking rifampin, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.Before using this medication, tell your doctor or pharmacist your medical history, especially of: diabetes, liver problems (e.g., hepatitis), HIV infection, history of alcohol use/abuse.This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.Before having surgery, tell your doctor or dentist that you are using this drug.During pregnancy, this medication should be used only when clearly needed. When this drug is taken during the last few weeks of pregnancy, the risk of bleeding in both mother and infant may be increased. Tell your doctor immediately if you notice any bleeding in your newborn. Discuss the risks and benefits with your doctor.Rifampin passes into breast milk. Consult your doctor before breast-feeding.
DRUG INTERACTIONS: Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop or change the dosage of any medicine before checking with them first.This drug should not be used with the following medications because very serious interactions may occur: live bacterial vaccines (e.g., oral typhoid), certain non-nucleoside reverse transcriptase inhibitors (nevirapine, delavirdine, etravirine), voriconazole, HIV protease inhibitors (e.g., saquinavir, ritonavir, indinavir).If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting rifampin.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use.This drug can speed up the removal of other drugs from your body by affecting certain liver enzymes. These affected drugs include (not a complete list): antiarrhythmics (e.g., disopyramide, mexiletine, quinidine), certain anti-cancer drugs (e.g., erlotinib, exemestane, imatinib, irinotecan), anticoagulants (e.g., warfarin, dicumarol), certain anti-infectives (e.g., chloramphenicol, clarithromycin, dapsone, doxycycline, linezolid, telithromycin, zidovudine, quinolones such as ciprofloxacin), certain antimalarial drugs (e.g., atovaquone, quinine), anti-seizure drugs (e.g., phenytoin, phenobarbital, lamotrigine), aprepitant, azole antifungals (e.g., itraconazole, ketoconazole), benzodiazepines (e.g., diazepam, midazolam), certain drugs to lower blood pressure (e.g., enalapril, certain beta blockers such as metoprolol and carvedilol, calcium channel blockers such as verapamil), caspofungin, corticosteroids (e.g., prednisone), certain oral drugs for diabetes (e.g., tolbutamide, chlorpropamide, repaglinide), digitoxin, certain hormone replacement drugs (e.g., estrogens such as conjugated estrogen, progestins such as medroxyprogesterone), certain drugs to suppress the immune system (e.g., cyclosporine, tacrolimus), certain drugs for mental/mood disorders (e.g., clozapine, haloperidol, tricyclic antidepressants such as amitriptyline), narcotic pain relievers (e.g., morphine, methadone), certain drugs for sleep (e.g., ramelteon, eszopiclone, zopiclone), certain statin drugs to lower cholesterol (e.g., atorvastatin, simvastatin), sulfasalazine, theophylline, thyroid medications (e.g., levothyroxine).This medication may decrease the effectiveness of hormonal birth control such as pills, patch, or ring. This could cause pregnancy. Discuss with your doctor or pharmacist if you should use additional reliable birth control methods while using this medication. Also tell your doctor if you have any new spotting or breakthrough bleeding, because these may be signs that your birth control is not working well.This medication may interfere with certain laboratory tests (urine screening for opiates, blood serum folate/vitamin B12), possibly causing false test results. Rifampin may also make it harder for your body to get rid of certain chemicals used in gallbladder tests. Make sure laboratory personnel and all your doctors know you use this drug.This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.
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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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