rifampin - oral, Rifadin, Rimactane (cont.)
HOW TO USE: This medication is best taken on an empty stomach with a full glass of water (8 ounces or 240 milliliters) 1 hour before or 2 hours after meals; or take as directed by your doctor. If you have nausea, do not take antacids with rifampin since it will lessen the effectiveness of this drug. However, if you need to take antacids, wait at least 1 hour after taking this drug.If you are unable to swallow the capsules, you may open the capsule and sprinkle the contents onto a spoonful of cool, soft applesauce or jelly. Eat the entire mixture immediately. Do not prepare a supply for future use.If you have a liquid form, shake the bottle well before each dose. Use a medication-measuring device to carefully measure the prescribed dose.Rifampin is frequently used in combination with other antibiotics to prevent or treat certain kinds of infections (e.g., latent/active tuberculosis, meningococcal disease). Your dose/schedule/treatment length will vary, depending on what you are treated for. Antibiotics work best when the amount of medicine in your body is kept at a constant level. Therefore, take this drug at evenly spaced intervals, or exactly as directed. Continue to take this medication until the full prescribed amount is finished, even if symptoms disappear after a few days. Stopping the medication too early may allow bacteria to continue to grow, which may result in a return of the infection.Inform your doctor if your condition persists or worsens.
SIDE EFFECTS: This drug may cause upset stomach, heartburn, nausea, menstrual changes, headache, drowsiness, or dizziness. If any of these effects persist or worsen, inform your doctor promptly.This medication may produce a harmless, reddish coloration of urine, sweat, saliva, or tears. Soft contact lenses may be permanently stained.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.Rifampin may infrequently cause serious liver disease. Though sometimes necessary to completely treat certain infections, combination treatment with other drugs (e.g., isoniazid, pyrazinamide) may increase this risk. Tell your doctor immediately if any of these unlikely but serious side effects occur: flu-like symptoms (fever, chills, headache, muscle aches), change in amount of urine, persistent nausea/vomiting, stomach/abdominal pain, dark urine, yellowing eyes/skin, mental/mood changes (e.g., confusion, unusual behavior), unusual tiredness, easy bruising/bleeding, small red spots on the skin, joint pain/swelling.This medication may rarely cause a severe intestinal condition (Clostridium difficile-associated diarrhea) due to a type of resistant bacteria. This condition may occur during treatment or weeks to months after treatment has stopped. Do not use anti-diarrhea products or narcotic pain medications if you have any of the following symptoms because these products may make them worse. Tell your doctor immediately if you develop: persistent diarrhea, abdominal or stomach pain/cramping, blood/mucus in your stool.Use of this medication for prolonged or repeated periods may result in oral thrush or a new yeast infection (oral/vaginal fungal infection). Contact your doctor if you notice white patches in your mouth, a change in vaginal discharge, or other new symptoms.In the unlikely event you have an allergic reaction to this drug, seek immediate medical attention. Symptoms of an allergic reaction include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Medically Reviewed by a Doctor on 4/16/2014
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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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