rifampin-injection, Rifadin (cont.)

DRUG INTERACTIONS: This drug is not recommended for use with: delavirdine. Ask your doctor or pharmacist for more details. Inform your doctor about all the medicines you may use (both prescription and nonprescription), especially of: warfarin, oral medicines for diabetes, azole antifungals (e.g., itraconazole, ketoconazole), theophylline, halothane, verapamil, certain protease inhibitors (e.g., nelfinavir), live vaccines, corticosteroids (e.g., prednisone), disopyramide, beta-blockers (e.g., metoprolol), isoniazid, digitoxin, quinidine, mexiletine, phenytoin, cyclosporine, zidovudine. Rifampin can decrease the effectiveness of oral contraceptives. Discuss the use of other birth control methods with your doctor. Also report drugs which cause drowsiness such as sedatives, tranquilizers, psychiatric medicines, anti-seizure or anti-anxiety drugs, narcotic pain relievers and certain antihistamines (e.g., diphenhydramine). Do not start or stop any medicine without doctor or pharmacist approval.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include swelling of face or around eyes, itching over the entire body, orange or red discoloration of skin or eyes, nausea, vomiting, drowsiness, and loss of consciousness.

NOTES: Laboratory tests will be done frequently to monitor the effectiveness of this medication and to prevent side effects.

MISSED DOSE: Try to use each dose at the scheduled time. If you miss a dose, use it as soon as remembered; do not use it if it is near the time for the next dose, instead, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.

STORAGE: The undiluted vials of this medication may be stored at room temperature as directed. If diluted in 10 ml, use within 24 hours. If diluted in 100 ml or 500 ml use within 4 hours. Check the expiration date on the label and properly discard of any unused medication after that date.

Last Editorial Review: 3/2/2005

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