RIFAMPIN - INJECTION (Rifadin) side effects, medical uses, and drug interactions.

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GENERIC NAME: RIFAMPIN - INJECTION (riff-AM-pin)

BRAND NAME(S): Rifadin

USES: This medication is used in the treatment of tuberculosis or other infections when the oral form cannot be taken. Use of only rifampin and pyrazinamide as a two-drug, two-month therapy to treat tuberculosis (specifically "latent" TB infection) is no longer recommended. Infrequently, serious (sometimes fatal) liver disease has occurred with the use of these two drugs alone. Several other effective alternative treatments can be used to treat latent tuberculosis (e.g., isoniazid for 9 months). Use of rifampin and pyrazinamide as part of a multi-drug (3 or more drugs) treatment plan for tuberculosis is still acceptable. Consult your doctor or pharmacist for more details.

HOW TO USE: This medication is given by injection into a vein usually once or twice a day. Avoid injecting intramuscularly or subcutaneously. Inject into a vein only. This medication must be used as prescribed. Do not skip doses or stop using this without your doctor's approval. Stopping therapy too soon may result in ineffective treatment. Full course of therapy may take several months or longer to complete.

SIDE EFFECTS: Sore mouth, drowsiness, dizziness or flushing may occur the first several days as your body adjusts to the medication. If any of these effects continue or become bothersome, inform your doctor. Tell your doctor immediately if any of these unlikely but serious side effects occur: weakness, unusual bruising or bleeding, flu-like symptoms (fever, chills, headache, muscle ache), nausea, vomiting, stomach pain, dark urine, yellowing of the eyes or skin, pale stools, numbness or tingling of the hands or feet, changes in vision, confusion, memory trouble, sore throat. This medication may cause urine, saliva, tears, stools and sweat to turn red-orange in color. Do not be alarmed. This will disappear when the medication is stopped. Notify your doctor if the injection site becomes swollen or irritated. Another injection site may be necessary. In the unlikely event you have an allergic reaction to this drug, seek immediate medical attention. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.