- What is ribavirin, and how does it work (mechanism of action)?
- What brand names are available for ribavirin?
- Do I need a prescription for ribavirin?
- What are the side effects of ribavirin?
- What is the dosage for ribavirin?
- Which drugs or supplements interact with ribavirin?
- Is ribavirin safe to take if I'm pregnant or breastfeeding?
- What else should I know about ribavirin?
What is the dosage for ribavirin?
- Ribavirin dosing is individualized based upon a patient's weight and previous use of interferon.
- Dosing also depends on the formulation used and the type of hepatitis C virus infection.
- The recommended dose of ribavirin tablets is 800 to 1200 mg divided every 12 hours for 24 to 48 weeks.
- Ribavirin may be taken with or without food. When taken orally, it should be taken consistently. For example, it should be taken at the same time or times each day and with or without food each time.
Which drugs or supplements interact with ribavirin?
Ribavirin used at the same time as other antiviral drugs with similar mechanisms of action may cause a condition in which lactic acid accumulates in the blood (lactic acidosis) which can lead to serious medical problems. Other such antiviral drugs include those used to manage HIV infection, for example, zidovudine (Retrovir), zalcitabine (Hivid) or stavudine (Zerit).
Adding ribavirin treatment among patients taking azathioprine (Imuran, Azasan) increases the chance of severe pancytopenia (a reduction in the numbers of all types of blood cells) due to azathioprine. This occurs because ribavirin reduces the breakdown of a harmful chemical produced during the breakdown of azathioprine.
Quick GuideHepatitis C (Hep C) Symptoms and Treatment
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