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Rhubarb can cause some side effects such as stomach and intestinal pain, watery diarrhea, and uterine contractions. Long-term use can result in muscular weakness, bone loss, potassium loss, and irregular heart rhythm.
There is a report of kidney failure in someone who took a rhubarb-containing product. But there is not enough information to know for sure if rhubarb was the actual cause of kidney failure.
Rhubarb might not be safe for children.
Do not use rhubarb if:
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.