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Quick GuideUnderstanding Cancer: Metastasis, Stages of Cancer, and More
What Causes Retinoblastoma?
Our eyes begin to develop very early in the womb. Rapidly growing cells in the eye, called retinoblasts, will eventually mature and form the retina, the light-sensing part of the eye that is located in the back of the eye. Sometimes, these specialized cells do not stop reproducing and form a tumor on the retina. These tumors may continue to grow, filling almost the entire vitreous humor (the jellylike substances the fills the eyeball). These tumors can also break off and spread to other parts of the eye, and eventually outside to lymph nodes and other organs.
Who Gets Retinoblastoma?
Retinoblastoma occurs most often in children 5 years and under. It rarely occurs in adults. Between 200 and 300 children are diagnosed with retinoblastoma each year, affecting one in every 20,000. About 40% of all cases of retinoblastoma are inherited, meaning the cancer is passed on from parent to child. Retinoblastoma occurs about 75% of the time in one eye, and 25% of the time in both eyes.
What Are the Symptoms of Retinoblastoma?
Symptoms of retinoblastoma include:
- A pupil that appears white when light is shone into it, called leucocoria, may mean that a retinal tumor is present. Blood vessels in the back of the eye will normally reflect red.
- The eyes may not move or focus in the same direction.
- Eye pain
- The pupil is constantly dilated.
- Red eye(s)
How Is Retinoblastoma Diagnosed?
An eye exam and imaging test given by an eye doctor can diagnose retinoblastoma.
If retinoblastoma is suspected, an ophthalmologist will need to examine the eye using special equipment to see the retina. Other tests may be conducted to determine the stage of the retinoblastoma, or how far it has spread. These tests include ultrasound, MRI scans, CT scans, bone scans, spinal tap, and bone marrow tests.