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November 24, 2009
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reteplase-injection (cont.)

PRECAUTIONS: This medication is not recommended for use if you have the following medical conditions: active internal bleeding (e.g., ulcer, trauma), history of stroke, recent surgery of the brain or spine, blood vessel problems (e.g., aneurysms), severe high blood pressure (uncontrolled). Tell your doctor your medical history, especially of: bleeding or blood problems, high blood pressure, diabetes, high cholesterol, blood clots (e.g., thrombophlebitis), recent surgery or injury, heart problems/infections (e.g., arrhythmias, endocarditis, mitral valve stenosis), eye problems, kidney or liver disease. This medication may cause you to bleed easily. Use caution with sharp objects like safety razors or nail cutters and avoid activities which that may increase your chance of getting cut, bruised, or injured. Also, avoid unnecessary injections into the muscles (IM). Caution is advised when using this drug in the elderly because they may be more sensitive to the effects of the drug. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known if this medication passes into breast milk. Consult your doctor before breast-feeding.

DRUG INTERACTIONS: Tell your doctor of all prescription and nonprescription medication you may use, especially: aspirin, abciximab, antiplatelet drugs (e.g., clopidogrel, dipyridamole, ticlopidine), "blood thinners" (e.g., warfarin or heparins), NSAIDs (e.g., ibuprofen, naproxen). This product can affect the results of certain lab tests. Make sure laboratory personnel and your doctors know you use this drug. Do not start or stop any medicine without doctor or pharmacist approval.




Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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