REPAGLINIDE-ORAL (cont.)
PRECAUTIONS: Tell your doctor your medical history, including: kidney disease, liver disease, adrenal or pituitary gland problems, any allergies. Unusual stresses such as fever, serious infection, trauma or surgery may result in loss of blood sugar control. Consult your doctor or pharmacist. Limit alcohol intake, as it may aggravate drug side effects. This medication should be used only when clearly needed during pregnancy. Insulin therapy may be necessary during pregnancy. Discuss the risks and benefits with your doctor. It is not known whether this drug is excreted into breast milk. Because of the potential risk to the infant, breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding. Caution is advised when this drug is used in the elderly since side effects may be aggravated and more difficult to recognize.
DRUG INTERACTIONS: Repaglinide should not be used with the following medication because very serious effects (very low blood sugar) may occur: gemfibrozil. If you are currently using this medication, tell your doctor or pharmacist before starting repaglinide. Fenofibrate may be an alternative medication for the gemfibrozil. Also, itraconazole should not be used in combination with repaglinide and gemfibrozil because extremely low blood sugar could occur. Tell your doctor of all nonprescription and prescription medication you may use, especially: beta-blocker type drugs (e.g., propranolol, metoprolol), NSAIDs (e.g., aspirin, ibuprofen), sulfa drugs (e.g., sulfamethoxazole), chloramphenicol, "blood thinners" (e.g., warfarin), probenecid, MAO Inhibitors (e.g., phenelzine, tranylcypromine, selegiline, furazolidone), "water pills" (e.g., thiazides, furosemide), corticosteroids, phenothiazines (e.g., chlorpromazine), thyroid drugs, estrogens and birth control pills, niacin, "adrenaline-like" drugs (e.g., pseudoephedrine), "calcium blockers" (e.g., verapamil), isoniazid (INH), drugs which affect certain liver enzymes (CYP 3A4 inhibitors and inducers such as azole antifungals- e.g., ketoconazole, macrolide antibiotics- e.g., clarithromycin, cimetidine, rifamycins- e.g., rifampin, St John's wort, certain anti-seizure medications- e.g., phenytoin). Check all medicine labels (including nonprescription drugs) since many products contain "adrenaline-like" drugs. Consult your pharmacist. Do not start or stop any medicine without doctor or pharmacist approval.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
- Drug Interactions - Learn about potential drug interactions you may be exposed to. Drug interactions can occur with prescription drugs, OTC medication, vitamins, herbs, and supplements.
- Hemoglobin A1c Test - Hemoglobin A1c test is used as a standard tool to determine blood sugar control for patients with diabetes
- Diabetes - Learn about type 1 and 2 diabetes (Diabetes Mellitus) symptoms including increased urination, thirst, weight loss, fatigue, nausea, vomiting, skin infections, and blurred vision. Causes and diagnosis information is provided in the information.
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