Table of Contents
- Raynaud's phenomenon facts
- What is Raynaud's phenomenon?
- What causes Raynaud's phenomenon?
- What are risk factors from Raynaud's phenomenon?
- What conditions have been associated with Raynaud's phenomenon?
- What are Raynaud's phenomenon symptoms and signs?
- What tests do health-care professionals use to diagnose Raynaud's phenomenon?
- What specialties of doctors treat Raynaud's phenomenon?
- What is the treatment for Raynaud's phenomenon?
- What is the prognosis (outlook) for Raynaud's phenomenon?
- Is it possible to prevent Raynaud's phenomenon?
- What research is being done on Raynaud's phenomenon?
Quick GuideLupus Symptoms, Rash, and Treatment
What causes Raynaud's phenomenon?
The causes of primary and secondary RP are unknown. Both abnormal nerve control of the blood-vessel diameter and nerve sensitivity to cold exposure have been suspected as being contributing factors. The characteristic color changes of the digits are in part related to initial blood-vessel narrowing due to spasm of the tiny muscles in the wall of the vessels, followed by sudden opening (dilation), as described above. The small arteries of the digits can have microscopic thickness of their inner lining, which also leads to abnormal narrowing of the blood vessels.
What are risk factors from Raynaud's phenomenon?
Risk factors for Raynaud's phenomenon include injury from frostbite and vibrating tools, medications (bleomycin [Blenoxane]), propranolol (Inderal), ergotamine), and having rheumatic diseases such as scleroderma, systemic lupus erythematosus, Sjögren's syndrome, mixed connective tissue disease, and rheumatoid arthritis.
What conditions have been associated with Raynaud's phenomenon?
Raynaud's phenomenon has been seen with a number of conditions, including rheumatic diseases (scleroderma, rheumatoid arthritis, systemic lupus erythematosus, and mixed connective tissue disease), hormone imbalance (hypothyroidism and carcinoid), trauma (frostbite, vibrating tools), medications (propranolol [Inderal], estrogens without additional progesterone, bleomycin [Blenoxane] used in cancer treatment, and ergotamine used for headaches), nicotine, and even rarely with cancers. Continue Reading
Kasper, D., et al., eds. Harrison's Principles of Internal Medicine, 19th Ed. United States: McGraw-Hill Professional, 2015.
Koopman, William, et al., eds. Clinical Primer of Rheumatology. Philadelphia: Lippincott Williams & Wilkins, 2003.
Ruddy, Shaun, et al., eds. Kelley's Textbook of Rheumatology, 6th ed. Philadelphia: Saunders, 2001.
2. "A thermal image demonstrating the loss of heat in a Reynaud's sufferer" by Joe m2013 - Own work. Licensed under CC0 via Wikimedia Commons
3. National Heart, Lung, and Blood Institute
4. eMedicineHealth - Image courtesy of Shabir Bhimji, MD / Tcal at English Wikipedia / Walt Fletcher at English Wikipedia
5. Getty Images
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