rasagiline, Azilect (cont.)

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Medical and Pharmacy Editor:

PRESCRIBED FOR: Rasagiline is used alone or in combination with levodopa to treat signs and symptoms of Parkinson's disease.

SIDE EFFECTS: The most common adverse effects of rasagiline are:

Rasagiline also may cause low or high blood pressure. A hypertensive crisis may occur if foods high in tyramine are consumed while taking rasagiline. Tyramine in food usually is broken down in the intestine by MAO-A in the intestinal wall as the tyramine is absorbed into the body. There are no adequate studies in humans to determine whether rasagiline also inhibits MAO-A; however, if MAO-A is inhibited, tyramine ingested in food may enter the body in larger amounts and result in a hypertensive crisis. Foods high in tyramine include those that are aged, fermented, pickled, or smoked. Examples include aged cheeses, air-dried meats, sauerkraut, soy sauce, tap/draft beers and red wines. As a precaution, foods high in tyramine should be avoided when taking rasagiline.

Medically Reviewed by a Doctor on 3/30/2015

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