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- What is raltegravir, and how does it work (mechanism of action)?
- What brand names are available for raltegravir?
- Is raltegravir available as a generic drug?
- Do I need a prescription for raltegravir?
- What are the uses for raltegravir?
- What are the side effects of raltegravir?
- What is the dosage for raltegravir?
- Which drugs or supplements interact with raltegravir?
- Is raltegravir safe to take if I'm pregnant or breastfeeding?
- What else should I know about raltegravir?
What is raltegravir, and how does it work (mechanism of action)?
- Raltegravir (Isentress) is an antiretroviral medicine approved for the treatment of human immunodeficiency virus (HIV) infection. Raltegravir is an integrase inhibitor similar to elvitegravir (Vitekta) and dolutegravir (Tivicay). Raltegravir slows the spread of HIV infection by blocking the HIV integrase enzyme required for virus multiplication. To improve the chance of fighting HIV-1 infection, raltegravir must be taken with other HIV medicines. Although raltegravir does not cure HIV or AIDS, continuous HIV treatment with raltegravir can help patients control the infection and decrease their risk of acquiring HIV-related illnesses. Raltegravir helps to improve the immune system by increasing the number of white blood cells called CD4+ (T) cells, and consequently reduce the risk of death or getting opportunistic infections that can happen when the immune system is weak.
- Raltegravir was initially approved by the FDA in October 2007.
What brand names are available for raltegravir?
Is raltegravir available as a generic drug?
GENERIC AVAILABLE: No
Do I need a prescription for raltegravir?
What are the uses for raltegravir?
Raltegravir is a prescription HIV medicine used with other antiretroviral medicines to treat human immunodeficiency virus-1 (HIV-1) infection in patients 4 weeks or age and older. Raltegravir does not cure the HIV-1 infection or AIDS. It works to reduce the viral load which is the amount of HIV virus in the blood.
What are the side effects of raltegravir?
The most common side effects of raltegravir include:
Other potential side effects of raltegravir include:
- Hepatitis (a type of viral infection of the liver)
- Blood disorders
- Kidney failure
- Kidney stones
- Indigestion or stomach pain
- Muscle pain (myopathy)
- Rhabdomyolysis (muscle destruction)
- Increased bilirubin
- Increased levels of liver enzymes
- Increased blood glucose
- Suicidal thoughts or actions
Some patients taking raltegravir experience serious skin and allergic reactions. These reactions can be severe or life-threatening if not treated promptly. Patients who develop any type of skin rash with other symptoms should call their doctor right away.
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Report Problems to the Food and Drug Administration
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