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Radiofrequency Ablation (RFA) Therapy of Liver


When do surgeons do RFA?

In the U.S., RFA therapy has become the ablation (tissue destruction) therapy of choice among surgeons for treating liver cancer (HCC). The surgeon can perform this procedure laparoscopically (through small holes in the abdomen) or during open exploration of the abdomen. In some instances, the procedure can be done without opening the abdomen by just using ultrasound for visual guidance.

How is RFA done and how does it work?

In RFA, heat is generated locally by a high frequency, alternating current that flows from the electrodes. A probe is inserted into the center of the tumor and the non-insulated electrodes, which are shaped like prongs, are projected into the tumor. The local heat that is generated melts the tissue (coagulative necrosis) that is adjacent to the probe. The probe is left in place for about 10 to 15 minutes. The whole procedure is monitored visually by ultrasound scanning.

What size tumor is treated by RFA?

The ideal size of an HCC tumor for RFA is less than 3 cm. Larger tumors may require more than one session.

What is the benefit of RFA therapy?

This treatment should be viewed as palliative (providing some relief), but not curative.

To read more about Hepatocellular Carcinoma (HCC), please read the MedicineNet.com Liver Cancer (Hepatocellular Carcinoma) article.

Medical Author: Tse-Ling Fong, M.D.
Medical Editor: Leslie J. Schoenfield, M.D., Ph.D.


Last Editorial Review: 4/24/2002




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Radiofrequency Ablation (RFA) Therapy of Liver

What is liver cancer (hepatocellular carcinoma, HCC)?

Liver cancer (hepatocellular carcinoma) is a cancer arising from the liver. It is also known as primary liver cancer or hepatoma. The liver is made up of different cell types (for example, bile ducts, blood vessels, and fat-storing cells). However, liver cells (hepatocytes) make up 80% of the liver tissue. Thus, the majority of primary liver cancers (over 90 to 95%) arises from liver cells and is called hepatocellular cancer or carcinoma.

When patients or physicians speak of liver cancer, however, they are often referring to cancer that has spread to the liver, having originated in other organs (such as the colon, stomach, pancreas, breast, and lung). More specifically, this type of liver cancer is called metastatic liver disease (cancer) or secondary liver cancer. Thus, the term liver cancer actually can refer to either metastatic liver cancer or hepatocellular cancer. The subject of this article i...

Read the Liver Cancer article »










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