pyridostigmine (Mestinon) (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

DRUG INTERACTIONS: Pyridostigmine should not be used with other cholinesterase inhibitors such as neostigmine (Bloxiverz, Prostigmin) or edrophonium (Tensilon, Enlon, Reversol) because of the risk of additive toxicity.

Use of quinine (Qualaquin) with pyridostigmine should be avoided as the actions of quinine on skeletal muscle are opposite to those of pyridostigmine.

PREGNANCY: The safety of pyridostigmine during pregnancy has not been evaluated. Therefore, pyridostigmine should only be used during pregnancy if the benefits of treatment outweigh the potential risk to the mother and the unborn baby. Pyridostigmine is classified as FDA pregnancy risk category C.

NURSING MOTHERS: Pyridostigmine can be excreted into human milk. The American Academy of Pediatrics considers pyridostigmine to be generally compatible with nursing. Pyridostigmine should be used cautiously in nursing mothers.

REFERENCE: FDA Prescribing Information.


Medically Reviewed by a Doctor on 5/11/2015


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