pygeum (Pygeum africanum)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Charles Patrick Davis, MD, PhD
    Charles Patrick Davis, MD, PhD

    Charles Patrick Davis, MD, PhD

    Dr. Charles "Pat" Davis, MD, PhD, is a board certified Emergency Medicine doctor who currently practices as a consultant and staff member for hospitals. He has a PhD in Microbiology (UT at Austin), and the MD (Univ. Texas Medical Branch, Galveston). He is a Clinical Professor (retired) in the Division of Emergency Medicine, UT Health Science Center at San Antonio, and has been the Chief of Emergency Medicine at UT Medical Branch and at UTHSCSA with over 250 publications.

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What is pygeum (Pygeum africanum)-oral, and how does it work (mechanism of action)?

Prunus africanum is a natural herbal supplement. Prunus africanum contains triterpenes, ferulic acid and phytosterols. Ferulic acid lowers prostatic cholesterol levels and phytosterols block prostaglandin synthesis, leading to reduced pain and inflammation. Triterpenes also blocks enzymes responsible for destruction of connective tissues, leading to possible improvement in symptoms of an enlarged prostate. Check with your health care professional before using herbs or herbal supplements.

What brand names are available for pygeum (Pygeum africanum)-oral?

Prunus africanum

Is pygeum (Pygeum africanum)-oral available as a generic drug?

GENERIC AVAILABLE: Yes

Do I need a prescription for pygeum (Pygeum africanum)-oral?

No

What are the side effects of pygeum (Pygeum africanum)-oral?

Side effects of Prunus africanum are nausea, abdominal pain, constipation, and diarrhea.

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What is the dosage for pygeum (Pygeum africanum)-oral?

The recommended dose of Prunus africanum by suppliers is 75 to 200 mg per day. Individuals should consult their doctor before taking Prunus africanum compounds.

Which drugs or supplements interact with pygeum (Pygeum africanum)-oral?

: Use with caution with other prostate medications such as finasteride (Proscar) and dutasteride (Avodart) to avoid additive side effects and potential harm.

Is pygeum (Pygeum africanum)-oral safe to take if I'm pregnant or breastfeeding?

It is not known whether Prunus africanum enters breast milk; therefore, it is best to be cautious before using it in mothers who are nursing.

What else should I know about pygeum (Pygeum africanum)-oral?

What preparations of pygeum (Pygeum africanum)-oral are available?

Prunus africanum is available in capsules, liquid extract, and powder form. Concentration of Prunus africanum may vary from product-to-product due to multiple manufacturers producing various products.

How should I keep pygeum (Pygeum africanum)-oral stored?

Due to multiple manufacturers making different forms of Prunus africanum, storage requirements may vary based on individual manufacturers practices. One commercial product requires storage in a cool dry place.

REFERENCES:

USDA Germplasm Resources Information Network. Genus: Pygeum Gaertn.

National Institutes of Health; Dietary Supplement Label Database. Pygeum Extract.

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Reviewed on 8/15/2014
References
REFERENCES:

USDA Germplasm Resources Information Network. Genus: Pygeum Gaertn.

National Institutes of Health; Dietary Supplement Label Database. Pygeum Extract.

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