In this Article
dizziness, gut problems, headache, and mouth ulcers.
Special Precautions & Warnings:Pregnancy and breast-feeding: Early research suggests that pycnogenol is POSSIBLY SAFE when used in late pregnancy. However, until more is known, pycnogenol should be used cautiously or avoided by women who are pregnant.
There is not enough reliable information about the safety of taking pycnogenol if you are breast-feeding. Stay on the safe side and avoid use.
Children: Pycnogenol is POSSIBLY SAFE when taken by mouth, short-term.
"Auto-immune diseases" such as multiple sclerosis (MS), lupus (systemic lupus erythematosus, SLE), rheumatoid arthritis (RA), or other conditions: Pycnogenol might cause the immune system to become more active, and this could increase the symptoms of auto-immune diseases. If you have one of these conditions, it's best to avoid using pycnogenol.
Bleeding conditions: In theory, high doses of pycnogenol might increase the risk of bleeding in people with bleeding conditions.
Diabetes: In theory, high doses of pycnogenol might decrease blood sugar too much in people with diabetes.
Surgery: Pycnogenol might slow blood clotting. There is some concern that it might increase the chance of bleeding during and after surgery. Stop using pycnogenol at least 2 weeks before a scheduled surgery.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.