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Pulmonary Hypertension (cont.)

What are primary and secondary pulmonary hypertension?

In the conventional classification, pulmonary hypertension, which is also called pulmonary arterial hypertension, is divided into two main categories; 1) primary pulmonary hypertension (not caused by any other disease or condition); and 2) secondary pulmonary hypertension (caused by another underlying condition). Secondary pulmonary hypertension is much more common than primary pulmonary hypertension.

A newer classification of this condition is based on the main underlying cause of pulmonary hypertension. This system classifies the condition based on whether it is due to:

  • left sided heart disease,

  • lung disease,

  • blood clots,

  • constriction of arteries due to any reasons (including primary pulmonary hypertension), and

  • obstruction from outside of blood vessel (for example from diseases of the chest wall compressing the blood vessels).

What causes pulmonary hypertension?

Pulmonary hypertension can be caused by diseases of the heart and the lungs, such as:

Other conditions that may cause pulmonary hypertension include:

Pulmonary hypertension can also be caused by chronic low blood oxygen levels as in some patients with sleep apnea or other long-standing (chronic) lung disease.

Again, pulmonary hypertension caused by these other illnesses can also be referred to as secondary pulmonary hypertension.

When pulmonary hypertension occurs without underlying heart and lung disease or other illnesses, it is called primary pulmonary hypertension. Primary pulmonary hypertension is more common in younger people and more in females than in males.

Recently this condition has been rarely reported with the use of anti-obesity drugs such as dexfenfluramine (Redux) and Fen/Phen. These medications have seen been removed from the market. Some street drugs such as, cocaine and methamphetamines can cause severe pulmonary hypertension.



Next: What causes primary pulmonary hypertension? »

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