Proton Pump Inhibitors (PPIs) (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

Proton pump inhibitors can reduce the break-down of some drugs by the liver and lead to an increase in their concentration in the blood. Omeprazole (Prilosec) is more likely than the other PPIs to reduce the break-down of drugs by the liver. For example, omeprazole (Prilosec) may increase the concentration in the blood of diazepam (Valium), warfarin (Coumadin) and phenytoin (Dilantin).

Which proton pump inhibitors (PPIs) are approved in the United States?

Available proton pump inhibitors  include:

Reference: FDA Prescribing Information


Last Editorial Review: 1/4/2011



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