Abnormal: Not normal. Deviating from the usual structure, position, condition, or behavior. In referring to a growth, abnormal may mean that it is cancerous or premalignant (likely to become cancer ).
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Aging: The process of becoming older, a process that is genetically determined and environmentally modulated.
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Antibody: An immunoglobulin, a specialized immune protein , produced because of the introduction of an antigen into the body, and which possesses the remarkable ability to combine with the very antigen that triggered its production.
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Antigen: A substance that is capable of causing the production of an antibody .
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Benign: Not cancer. Not malignant . A benign tumor does not invade surrounding tissue or spread to other parts of the body. A benign tumor may grow but it stays put (in the same place).
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Biopsy: The removal of a sample of tissue for purposes of diagnosis. (Many definitions of "biopsy" stipulate that the sample of tissue is removed for examination under a microscope. This may or may not be the case. The diagnosis may be achieved by other means such as by analysis of chromosomes or genes.)
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Bladder: Any pouch or other flexible enclosure that can hold liquids or gases but usually refers to the hollow organ in the lower abdomen that stores urine -- the urinary bladder. The kidneys filter waste from the blood and produce urine, which enters the bladder through two tubes called ureters. Urine leaves the bladder through another tube, the urethra . In women, the urethra is a short tube that opens just in front of the vagina . In men, it is longer, passing through the prostate gland and then the penis . Infection of the bladder is called cystitis .
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Blood: The familiar red fluid in the body that contains white and red blood cells, platelets, proteins, and other elements. The blood is transported throughout the body by the circulatory system. Blood functions in two directions: arterial and venous. Arterial blood is the means by which oxygen and nutrients are transported to tissues while venous blood is the means by which carbon dioxide and metabolic by-products are transported to the lungs and kidneys, respectively, for removal from the body.
BPH: Benign prostatic hyperplasia which is also known as benign prostatic hypertrophy. Nonmalignant enlargement of the prostate gland.
Cancer: An abnormal growth of cells which tend to proliferate in an uncontrolled way and, in some cases, to metastasize (spread).
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Condition: The term "condition" has a number of biomedical meanings including the following: - An unhealthy state, such as in "this is a progressive condition."
- A state of fitness, such as "getting into condition."
- Something that is essential to the occurrence of something else; essentially a "precondition."
- As a verb: to cause a change in something so that a response that was previously associated with a certain stimulus becomes associated with another stimulus; to condition a person, as in behavioral conditioning.
Digital rectal exam (DRE): An exam to detect abnormalities that can be felt (palpated) from within the rectum. The doctor inserts a lubricated, gloved finger into the rectum and feels for anything that is not normal.
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Disease: Illness or sickness often characterized by typical patient problems (symptoms) and physical findings (signs). Disruption sequence: The events that occur when a fetus that is developing normally is subjected to a destructive agent such as the rubella (German measles) virus.
Gland: 1. A group of cells that secrete a substance for use in the body. For example, the thyroid gland. 2. A group of cells that removes materials from the circulation. For example, a lymph gland.
Hyperplasia: A condition in which there is an increase in the number of normal cells in a tissue or organ.
Hypertrophy: Enlargement or overgrowth of an organ or part of the body due to the increased size of the constituent cells. Hypertrophy occurs in the biceps and heart because of increased work. Cardiac hypertrophy is recognizable microscopically by the increased size of the cells. The term hypertrophy is applied to the enlargement of the uterus during pregnancy. The term benign prostatic hypertrophy is a misnomer because the increased size of the prostate is due to hyperplasia, an increase in the number of cells.
Infection: The growth of a parasitic organism within the body. (A parasitic organism is one that lives on or in another organism and draws its nourishment therefrom.) A person with an infection has another organism (a "germ") growing within him, drawing its nourishment from the person.
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Laboratory: A place for doing tests and research procedures and preparing chemicals, etc. Although "laboratory" looks very like the Latin "laboratorium" (a place to labor, a work place), the word "laboratory" came from the Latin "elaborare" (to work out, as a problem, and with great pains), as evidenced by the Old English spelling "elaboratory" designating "a place where learned effort was applied to the solution of scientific problems."
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Marker: A piece of DNA that lies on a chromosome so close to a gene that the marker and the gene are inherited together. A marker is thus an identifiable heritable spot on a chromosome. A marker can be an expressed region of DNA (a gene) or a segment of DNA with no known coding function. All that matters is that the marker can be detected and trailed.
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Monoclonal: Pertaining to a single clone of cells, a single cell and the progeny of that cell. As opposed to polyclonal.
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Monoclonal antibody: An antibody produced by a single clone of cells (specifically, a single clone of hybridoma cells) and therefore a single pure homogeneous type of antibody. Monoclonal antibodies can be made in large amounts in the laboratory and are a cornerstone of immunology. The term "monoclonal" pertains to a single clone of cells, a single cell and the progeny of that cell.
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Probability: The likelihood that something will happen. For example, a probability of less than .05 indicates that the probability of something occurring by chance alone is less than 5 in 100, or 5 percent. This level of probability is usually taken as the level of biologic significance, so a higher incidence may be considered meaningful. The abbreviation for probability is P.
Prostate: A gland within the male reproductive system that is located just below the bladder. Chestnut shaped, the prostate surrounds the beginning of the urethra, the canal that empties the bladder.
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Prostate cancer: An uncontrolled (malignant) growth of cells in the prostate gland which is located at the base of the urinary bladder and is responsible for helping control urination as well as forming part of the semen. Prostate cancer is the second leading cause of death of males in the U.S.
Prostate gland: A gland within the male reproductive system that is located just below the bladder. Chestnut shaped, the prostate surrounds the beginning of the urethra, the canal that empties the bladder.
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Prostate specific antigen: Widely known as PSA. See: PSA.
Prostatectomy: The surgical removal of the prostate gland.
Prostatitis : Inflammation of the prostate gland, a very common health concern, accounting for up to 25% of all medical office visits by young and middle-age men for problems relating to the genital and urinary systems.
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Protein: A large molecule composed of one or more chains of amino acids in a specific order determined by the base sequence of nucleotides in the DNA coding for the protein.
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Proteins: Large molecules composed of one or more chains of amino acids in a specific order determined by the base sequence of nucleotides in the DNA coding for the protein.
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PSA: Prostate specific antigen . A test for PSA may be used to screen for cancer of the prostate and to monitor treatment of the disease.
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Rectum: The last 6 to 8 inches of the large intestine. The rectum stores solid waste until it leaves the body through the anus. The word rectum comes from the Latin rectus meaning straight (which the human rectum is not).
Recurrence: The return of a sign, symptom or disease after a remission. The reappearance of cancer cells at the same site or in another location is, unfortunately, a familiar form of recurrence.
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Semen: The fluid that is released through the penis during orgasm. Semen is made up of fluid and of sperm. The fluid comes from the prostate, seminal vesicle and other sex glands. The sperm are manufactured in the testicles. The seminal fluid helps transport the sperm during orgasm. Seminal fluid contains sugar as an energy source for sperm.
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Substance: 1. Material with particular features, as a pressor substance.
2. The material that makes up an organ or structure. Also known in medicine as the substantia.
3. A psychoactive drug as, for example, in substance abuse.
Therapy: The treatment of disease .
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Tumor: An abnormal mass of tissue. Tumors are a classic sign of inflammation, and can be benign or malignant (cancerous). There are dozens of different types of tumors. Their names usually reflect the kind of tissue they arise in, and may also tell you something about their shape or how they grow. For example, a medulloblastoma is a tumor that arises from embryonic cells (a blastoma) in the inner part of the brain (the medulla). Diagnosis depends on the type and location of the tumor. Tumor marker tests and imaging may be used; some tumors can be seen (for example, tumors on the exterior of the skin) or felt (palpated with the hands).
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Tumor marker: Tumor markers are substances that can be detected in higher-than-normal amounts in the blood, urine, or body tissues of some patients with certain types of cancer . A tumor marker may be made by a tumor itself or by the body in response to the tumor. Such a substance serves to "mark" the tumor; it is a "tumor marker."
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Urethra: The transport tube leading from the bladder to discharge urine outside the body. In males, the urethra travels through the penis, and carries semen as well as urine. In females, the urethra is shorter than in the male and emerges above the vaginal opening, as indicated here:
Urinary: Having to do with the kidneys, ureters, and bladder. The urinary system represents the functional and anatomic aspects of the kidneys, ureters, and bladder.
- Prostate Cancer Screening - Get information on prostate cancer screening and prevention, risk factors, PSA testing, prostate exam, and other tests that screen and detect for prostate cancer. BPH has symptoms similar to prostate cancer.
- Prostatitis - Read about prostatitis, a painful infection of the prostate gland. Symptoms include fever, chills, painful urination, lower back pain, pain in the genital area, and frequent urination.
- Prostate Cancer - Learn about prostate cancer treatment, causes, signs, stages, hormone therapy, symptoms, and how to maintain good prostate health.
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