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November 25, 2009
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Prostate Cancer Screening (cont.)

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Prostate cancer is the most common nonskin cancer among men in the United States.

Prostate cancer is found mainly in older men. Although the number of men with prostate cancer is large, most men diagnosed with this disease do not die from it. In black men, however, prostate cancer is usually more advanced and they are more likely than white men to die from the disease.

Age, race, and family history of prostate cancer can affect the risk of developing prostate cancer.

Anything that increases a person's chance of developing a disease is called a risk factor. Risk factors for prostate cancer include the following:

Being 50 years of age or older. Being black. Having a brother, son, or father who had prostate cancer. Eating a diet high in fat or drinking alcoholic beverages.

Tests are used to screen for different types of cancer.

Some screening tests are used because they have been shown to be helpful both in finding cancers early and decreasing the chance of dying from these cancers. Other tests are used because they have been shown to find cancer in some people; however, it has not been proven in clinical trials that use of these tests will decrease the risk of dying from cancer.

Scientists study screening tests to find those with the fewest risks and most benefits. Cancer screening trials also are meant to show whether early detection (finding cancer before it causes symptoms) decreases a person's chance of dying from the disease. For some types of cancer, finding and treating the disease at an early stage may result in a better chance of recovery.

There is no standard or routine screening test for prostate cancer.

Screening tests for prostate cancer are under study, and there are screening clinical trials taking place in many parts of the country. Information about ongoing clinical trials is available from the NCI Cancer.gov Web site.

Tests to detect (find) prostate cancer that are being studied include the following:

Digital rectal exam

Digital rectal exam (DRE) is an exam of the rectum. The doctor or nurse inserts a lubricated, gloved finger into the lower part of the rectum to feel the prostate for lumps or anything else that seems unusual.

Picture of a digital rectal exam (DRE)
Digital rectal exam (DRE). The doctor inserts a gloved, lubricated finger into the rectum and feels the prostate to check for anything abnormal.


Prostate-specific antigen test

A prostate-specific antigen (PSA) test is a test that measures the level of PSA in the blood. PSA is a substance made mostly by the prostate that may be found in an increased amount in the blood of men who have prostate cancer. The level of PSA may also be high in men who have an infection or inflammation of the prostate or benign prostatic hyperplasia (BPH; an enlarged, but noncancerous, prostate).

Scientists are studying the combination of PSA testing and digital rectal exam as a way to get more accurate results from the screening tests.



Next: What are the risks of prostate cancer screening tests? »

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