propranolol, Inderal, Inderal LA, Innopran XL (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

PREGNANCY: Safe use during pregnancy has not been established. Growth retardation and congenital abnormalities have been reported in infants whose mothers received propranolol during pregnancy. Infants whose mothers received propranolol during labor have exhibited slow heart rate, hypoglycemia, and/or respiratory depression.

NURSING MOTHERS: Propranolol is secreted into breast milk. Is should be avoided or used with caution in nursing women.

SIDE EFFECTS: Side effects include abdominal cramps, diarrhea, constipation, fatigue, insomnia, nausea, depression, dreaming, memory loss, fever, impotence, lightheadedness, slow heart rate, low blood pressure, cold extremities, sore throat, and shortness of breath or wheezing. Propranolol can aggravate breathing difficulties in patients with asthma, chronic bronchitis, or emphysema. In patients with existing slow heart rates (bradycardias) and heart blocks (defects in the electrical conduction of the heart), propranolol can cause dangerously slow heart rates, and even shock. Propranolol reduces the force of heart muscle contraction and can aggravate symptoms of heart failure. In patients with coronary artery disease, abruptly stopping propranolol can suddenly worsen angina, and occasionally precipitate heart attacks. If it is necessary to discontinue propranolol, its dosage should be reduced gradually over several weeks.

REFERENCES: FDA Prescribing Information for Inderal

FDA Prescribing Information for Inderal


Last Editorial Review: 6/14/2010



Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Pill Finder Tool

Need help identifying pills and medications?
Use the pill identifier tool on RxList.


Back to Medications Index