Drugs which both stimulate and block opioid receptors, for example pentazocine (Talwin), nalbuphine (Nubain), butorphanol (Stadol), and buprenorphine (Buprenex) may reduce the effect of propoxyphene and may precipitate propoxyphene withdrawal symptoms.
PREGNANCY: There are no adequate studies of propoxyphene in pregnant women.
NURSING MOTHERS: Low concentrations of propoxyphene have been measured in the breast milk of mothers taking propoxyphene. It is not known whether these small amounts can cause side effects in nursing infants.
SIDE EFFECTS: The most frequent adverse reactions of propoxyphene include lightheadedness, dizziness, sedation, nausea, and vomiting. Other side effects include drowsiness, constipation, and spasm of the ureter, which can lead to difficulty in urinating.
Quick GuideChronic Pain: Causes, Solutions and Management
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