propoxyphene, Darvon, Darvon-N, Dolene (cont.)



PREPARATIONS: Tablet: 100 mg; Capsules: 65 mg

STORAGE: Capsules and tablets should be stored at room temperature, between 15- 30 C (59-86 F).

PRESCRIBED FOR: Propoxyphene is used for the treatment of mild to moderate pain.

DOSING: The recommended adult dose is 1 capsule (65 mg) or 1 tablet (100 mg) every 4 hours as needed for relief of pain. Doses should not exceed 390 mg (capsule) or 600 mg (tablets) in a 24-hour period.

DRUG INTERACTIONS: Propoxyphene, like other narcotic pain-relievers, increases the effect of drugs that slow brain function, such as alcohol, barbiturates, skeletal muscle relaxants, for example, carisoprodol (Soma) and cyclobenzaprine (Flexeril), and benzodiazepine sedatives, for example, diazepam (Valium) and lorazepam (Ativan). Combined use of muscle relaxants and propoxyphene may lead to increased respiratory depression.

Combining propoxyphene with carbamazepine (Tegretol, Tegretol XR, Equetro, Carbatrol) may have extreme effects on the brain including coma.

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