propoxyphene, Darvon, Darvon-N, Dolene

Discontinued Warning Icon Please Note: propoxyphene, (Darvon, Darvon-N, Dolene) has been withdrawn from the U.S. market. Click here for the FDA information.

Pharmacy Author: Omudhome Ogbru, PharmD
Medical and Pharmacy Editor: Jay W. Marks, MD

GENERIC NAME: propoxyphene

BRAND NAME: Darvon, Darvon-N, Dolene

DRUG CLASS AND MECHANISM: Propoxyphene is a narcotic pain-reliever and cough suppressant but is weaker than morphine, codeine, and hydrocodone. The precise mechanism of action is not known but may involve stimulation of opioid (narcotic) receptors in the brain. Propoxyphene increases pain tolerance and decreases discomfort but the presence of pain still is apparent. In addition to pain reduction, propoxyphene also causes sedation and respiratory depression. The FDA approved propoxyphene in August 1957.

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