propafenone (Rythmol, Rythmol SR)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

GENERIC NAME: propafenone

BRAND NAME: Rythmol, Rythmol SR

PRESCRIPTION: Yes

GENERIC AVAILABLE: Yes

USES:

  • Propafenone is an anti-arrhythmic agent approved for use in patients with life-threatening ventricular arrhythmias, such as ventricular tachycardia.
  • Propafenone is also effective in suppressing the recurrence of atrial fibrillation and supra-ventricular tachycardia once normal sinus rhythm has been restored.
  • Propafenone is at least as effective as any other type I agent in converting atrial fibrillation to normal sinus rhythm.
  • Propafenone is effective in atrial tachycardia, AV nodal tachycardia, and bypass tract tachycardias.

SIDE EFFECTS:

Common side effects of propafenone are:

Serious side effects of propafenone include:

Because of its beta blocking activity, propafenone must be used with caution in patients with weak heart muscle (congestive heart failure), slow heart rate, any form of heart electrical conduction block, low blood pressure, or asthma.

The most serious side effect of propafenone is the causing of serious life- threatening irregular heart rhythms (ventricular arrhythmias or pro-arrhythmia) or heart block. It is for this reason that propafenone is started and doses increased while patients are hospitalized in a monitored setting.

Medically Reviewed by a Doctor on 9/16/2016

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