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Lab-made progesterone is used to imitate the functions of the progesterone released by the ovaries.
edema), fatigue, acne, drowsiness or insomnia, allergic skin rashes, hives, fever, headache, depression, breast discomfort or enlargement, premenstrual syndrome (PMS)-like symptoms, altered menstrual cycles, irregular bleeding, and other side effects.
Special Precautions & Warnings:Pregnancy and breast-feeding: Intravaginal progesterone gel is LIKELY SAFE when used as part of infertility treatment. However, progesterone is LIKELY UNSAFE when used during pregnancy for any other purpose.
There is not enough reliable information about the safety of taking progesterone if you are breast-feeding. Stay on the safe side and avoid use.
Arterial disease: Don't use progesterone if you have arterial disease.
Breast cancer: Avoid use unless you are directed to do so by your healthcare provider.
Depression: Get your healthcare provider's advice first before using progesterone if you have major depression now or a history of major depression.
Liver disease: Progesterone might make liver disease worse. Don't use it.
Vaginal bleeding: If you have undiagnosed vaginal bleeding, don't use progesterone.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.