progesterone (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

DOSING: Prevention of Endometrial Hyperplasia: 200 mg by mouth once daily at bedtime for 12 consecutive days per 28 day cycle. Treatment of Secondary Amenorrhea: 400 mg by mouth once daily at bedtime for 10 days.

DRUG INTERACTIONS: Progesterone should be used with caution with ketoconazole (Nizoral), clarithromycin (Biaxin), and erythromycin (Ery-Tab) because they slow the breakdown of progesterone and increase its levels in the body.

PREGNANCY: Progesterone should not be used during pregnancy.

NURSING MOTHERS: Progesterone may be found in trace amounts in breast milk in women taking progesterone capsules.

SIDE EFFECTS: Side effects of progesterone are headache, dizziness, fatigue, abdominal pain, nausea, breast tenderness, joint pain, depression, mood swings, and hot flashes.

Progesterone also isassociated with cardiovascular disorders, breast cancer, and possibly dementia in postmenopausal women.

REFERENCE: FDA Prescribing Information
Progesterone – Medscape

Medically Reviewed by a Doctor on 10/7/2014

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