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Probiotics Glossary of Terms

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Absorption: Uptake. In the biomedical sciences, absorption has diverse specific meanings.
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Acidophilus: Bacteria found in yogurt that can help restore a supportive bacterial environment to an intestinal tract whose normal intestinal bacterial population ("flora") has been disturbed by disease or antibiotics.
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Alternative medicine: Healing arts not taught in traditional Western medical schools that promote options to conventional medicine that is taught in these schools.. An example of an alternative therapy is using a special diet to treat cancer instead of undergoing surgery, radiation, or chemotherapy that has been recommended by a Western physician. Complementary medicine is different from alternative medicine. Whereas complementary medicine is used together with conventional medicine, alternative medicine is used in place of conventional medicine. See also complementary medicine, conventional medicine.

Atopic: Prone to allergies or characterized by allergy.

Atopic dermatitis: A skin disease characterized by areas of severe itching, redness, scaling, and loss of the surface of the skin (excoriation). When the eruption (rash) has been present for a prolonged time, chronic changes occur due to the constant scratching and rubbing known as lichenification (thickening of the skin with accentuation of the skin lines to form a crisscross pattern).
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Bacteria: Single-celled microorganisms which can exist either as independent (free-living) organisms or as parasites (dependent upon another organism for life).
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Bacterial: Of or pertaining to bacteria. For example, a bacterial lung infection.

Bacterium: The singular of bacteria.

Bladder: Any pouch or other flexible enclosure that can hold liquids or gases but usually refers to the hollow organ in the lower abdomen that stores urine -- the urinary bladder. The kidneys filter waste from the blood and produce urine, which enters the bladder through two tubes called ureters. Urine leaves the bladder through another tube, the urethra. In women, the urethra is a short tube that opens just in front of the vagina. In men, it is longer, passing through the prostate gland and then the penis. Infection of the bladder is called cystitis.

Bladder cancer: A common form of cancer that begins in the lining of the bladder as a superficial tumor (carcinoma in situ). The most common warning sign is blood in the urine. If there is enough blood to color the urine it may range from slightly rusty to deep red. Other symptoms may be pain during urination and frequent urination or feeling the need to urinate without results.
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Bowel: Another name for the intestine. The small bowel and the large bowel are the small intestine and large intestine, respectively.
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Cancer: An abnormal growth of cells which tend to proliferate in an uncontrolled way and, in some cases, to metastasize (spread).
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Cell: The basic structural and functional unit in people and all living things. Each cell is a small container of chemicals and water wrapped in a membrane.
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Chronic: This important term in medicine comes from the Greek chronos, time and means lasting a long time.
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Clinical trials: Trials to evaluate the effectiveness and safety of medications or medical devices by monitoring their effects on large groups of people.
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Clostridium: A group of anaerobic bacteria (bacteria that thrive in the absence of oxygen). There are 100+ species of Clostridium. They include, for examples, Clostridium difficile, Clostridium perfringens (also called Clostridium welchii), and Clostridium botulinum.
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Clostridium difficile: A bacterium that is one of the most common causes of infection of the large bowel (colon). In technical terms, Clostridium difficile (C. difficile) is an obligate anaerobic or microaerophilic, gram-positive, spore-forming, rod-shaped bacillus.
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Colitis: Inflammation of the large intestine (the colon). There are many forms of colitis, including ulcerative colitis, Crohn's disease, infectious, pseudomembranous, and spastic. For example, intermittent rectal bleeding, crampy abdominal pain and diarrhea can be symptoms of ulcerative colitis. Diagnosis can be made by barium enema, but direct visualization (sigmoidoscopy or colonoscopy) is the most accurate test. Long-standing ulcerative colitis increases the risk for colon cancer. Ulcerative colitis can also be associated with inflammation in joints, spine, skin, eyes, the liver and its bile ducts. Treatment of ulcerative colitis can involve medications and surgery.

Colon: The part of the large intestine that runs from the cecum to the rectum as a long hollow tube that serves to remove water from digested food and let the remaining material, solid waste called stool, move through it to the rectum and leave the body through the anus. .
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Crohn's disease: A chronic inflammatory disease, primarily involving the small and large intestine, but which can affect other parts of the digestive system as well. It is named for Burrill Crohn, the American gastroenterologist who first described the disease in 1932.
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Dermatitis: Inflammation of the skin, either due to direct contact with an irritating substance, or to an allergic reaction. Symptoms of dermatitis include redness, itching, and in some cases blistering.
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Diarrhea: A familiar phenomenon with unusually frequent or unusually liquid bowel movements, excessive watery evacuations of fecal material. The opposite of constipation. The word "diarrhea" with its odd spelling is a near steal from the Greek "diarrhoia" meaning "a flowing through." Plato and Aristotle may have had diarrhoia while today we have diarrhea. There are myriad infectious and noninfectious causes of diarrhea.
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Eczema: A particular type of inflammatory reaction of the skin in which there are typically vesicles (tiny blister-like raised areas) in the first stage followed by erythema (reddening), edema (swelling), papules (bumps), and crusting of the skin followed, finally, by lichenification (thickening) and scaling of the skin. Eczema characteristically causes itching and burning of the skin.
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Enzyme: A protein (or protein-based molecule) that speeds up a chemical reaction in a living organism. An enzyme acts as catalyst for specific chemical reactions, converting a specific set of reactants (called substrates) into specific products. Without enzymes, life as we know it would not exist.
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Gastrointestinal: Adjective referring collectively to the stomach and small and large intestines.
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Gene: The basic biological unit of heredity. A segment of deoxyribonucleic acid (DNA) needed to contribute to a function.
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Gene transfer: The insertion of unrelated genetic information in the form of DNA into cells.
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Genetic: Having to do with genes and genetic information.

Genital: Pertaining to the external and internal organs of reproduction. (Not to be confused with genetic.)

Helicobacter pylori: Bacteria that cause stomach inflammation (gastritis) and ulcers in the stomach. This bacteria is the most common cause of ulcers worldwide. It is often referred to as H. pylori.
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Immune: Protected against infection. The Latin immunis means free, exempt.

Immune system: A complex system that is responsible for distinguishing us from everything foreign to us, and for protecting us against infections and foreign substances. The immune system works to seek and kill invaders.
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Immunity: The condition of being immune. Immunity can be innate (for example, humans are innately immune to canine distemper) or conferred by a previous infection or immunization.

Infection: The growth of a parasitic organism within the body. (A parasitic organism is one that lives on or in another organism and draws its nourishment therefrom.) A person with an infection has another organism (a "germ") growing within him, drawing its nourishment from the person.
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Inflammation: A basic way in which the body reacts to infection, irritation or other injury, the key feature being redness, warmth, swelling and pain. Inflammation is now recognized as a type of nonspecific immune response.
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Inflammatory bowel disease: A group of chronic intestinal diseases characterized by inflammation of the bowel -- the large or small intestine. The most common types of inflammatory bowel disease (IBD) are ulcerative colitis and Crohn disease.
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Insertion: Chromosome abnormality due to insertion of a segment from one chromosome into another chromosome.

Kidney: One of a pair of organs located in the right and left side of the abdomen which clear "poisons" from the blood, regulate acid concentration and maintain water balance in the body by excreting urine. The kidneys are part of the urinary tract. The urine then passes through connecting tubes called "ureters" into the bladder. The bladder stores the urine until it is released during urination.

Lactobacillus: A bacterium normally found in the mouth, intestinal tract, and vagina. Lactobacillus can also live in fermenting products, such as yogurt. Humans appear to have a symbiotic relationship with this bacteria. Lactobacillus has been with us so long that some types have become an important part of food digestion, although Lactobacillus can also contribute to cavities in the teeth if allowed to remain too long within the mouth.

Lactobacillus acidophilus: The bacteria found in milk and fermented milk products, particularly yogurt with "live cultures" of L. acidophilus. L. acidophilus assists with the digestive process within the intestinal tract. It can be decimated by the use of antibiotics, and many health professionals urge people to use probiotics to counter this unfortunate side effect of antibiotic use.
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Lactose: The sugar found in milk. Lactose is a large sugar molecule that is made up of two smaller sugar molecules, glucose and galactose. In order for lactose to be absorbed from the intestine and into the body, it must first be split into glucose and galactose. The glucose and galactose are then absorbed by the cells lining the small intestine. The enzyme that splits lactose into glucose and galactose is called lactase, and it is located on the surface of the cells lining the small intestine.
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Lactose intolerance: Inability to digest lactose, a component of milk and most other dairy products. Lactose is sometimes also used as an ingredient in other foods, so those with a lactase deficiency should check labels carefully.
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Metabolic: Relating to metabolism, the whole range of biochemical processes that occur within us (or any living organism). Metabolism consists of anabolism (the buildup of substances) and catabolism (the breakdown of substances).
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Microscope: An optical instrument that augments the power of the eye to see small objects. The name microscope was coined by Johannes Faber (1574-1629) who in 1628 borrowed from the Greek to combined micro-, small with skopein, to view. Although the first microscopes were simple microscopes, most (if not all) optical microscopes today are compound microscopes.

Mouth: 1. The upper opening of the digestive tract, beginning with the lips and containing the teeth, gums, and tongue. Foodstuffs are broken down mechanically in the mouth by chewing and saliva is added as a lubricant. Saliva contains amylase, an enzyme that digests starch. 2. Any opening or aperture in the body. The mouth in both senses of the word is also called the os, the Latin word for an opening, or mouth. The o in os is pronounced as in hope. The genitive form of os is oris from which comes the word oral.

Mucous: Pertaining to mucus, a thick fluid produced by the lining of some tissues of the body.
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NCCAM: National Center for Complementary & Alternative Medicine.

NIH: The National Institutes of Health. The NIH is an important U.S. health agency. It is devoted to medical research. Administratively under the Department of Health and Human Services (HHS), the NIH consists of 20-some separate Institutes and Centers. NIH's program activities are represented by these Institutes and Centers.
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Nursing: 1) Profession concerned with the provision of services essential to the maintenance and restoration of health by attending the needs of sick persons. 2) Feeding a infant at the breast.

Periodontal: The word "periodontal" literally means "around the tooth." Periodontal diseases are bacterial infections that destroy the attachment fibers and supporting bone that hold the teeth in the mouth. Left untreated, these diseases can lead to tooth loss. The main cause of periodontal disease is a bacterial plaque, a sticky, colorless film that constantly forms on teeth.
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Periodontal disease: A bacterial infection that destroys the attachment fibers and supporting bone that hold the teeth in the mouth. Left untreated, these diseases can lead to tooth loss. The main cause of periodontal disease is bacterial plaque, a sticky, colorless film that constantly forms on teeth.

Placebo: A "sugar pill" or any dummy medication or treatment.
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Placebo effect: Also called the placebo response. A remarkable phenomenon in which a placebo -- a fake treatment, an inactive substance like sugar, distilled water, or saline solution -- can sometimes improve a patient's condition simply because the person has the expectation that it will be helpful. Expectation to plays a potent role in the placebo effect. The more a person believes they are going to benefit from a treatment, the more likely it is that they will experience a benefit.
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Probiotic: A microbe that protects its host and prevents disease. The best-known probiotic is Lactobacillus acidophilus, which is found in yogurt, acidophilus milk, and supplements. Probiotics counter the decimation of helpful intestinal bacteria by antibiotics. Probiotics given in combination with antibiotics are therefore useful in preventing antibiotic-associated diarrhea. The yeast S. boulardii and three strains of Lactobacillus have also been shown to be useful in this regard.

Probiotics: live microorganisms (usually bacteria) that are similar to beneficial microorganisms found in the human gut that are taken as dietary supplements or found in foods. Most probiotics are bacteria similar to those naturally found in the intestine. Common examples are Lactobacillus and Bifidobacterium . They may occur naturally in yogurts and certain fermented foods. Probiotics have been used as treatment for various gastrointestinal conditions including irritable bowel syndrome and traveler's diarrhea.

Public health: The approach to medicine that is concerned with the health of the community as a whole. Public health is community health. It has been said that: "Health care is vital to all of us some of the time, but public health is vital to all of us all of the time."
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Recurrence: The return of a sign, symptom or disease after a remission. The reappearance of cancer cells at the same site or in another location is, unfortunately, a familiar form of recurrence.
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Respiratory: Having to do with respiration, the exchange of oxygen and carbon dioxide. From the Latin re- (again) + spirare (to breathe) = to breathe again.

Rotavirus (RV): A leading cause of severe winter diarrhea in young children, RV each year causes an estimated 500,000 doctor visits and 50,000 hospital admissions in the United States. Almost everyone catches RV before entering school but, with rehydration (and good nutrition), nearly all recover fully. However, in poor countries it is estimated that there are at least 600,000 deaths of children under 5 years from RV diarrhea and dehydration.
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Shock: In medicine, shock is a critical condition brought on by a sudden drop in blood flow through the body. There is failure of the circulatory system to maintain adequate blood flow. This sharply curtails the delivery of oxygen and nutrients to vital organs. It also compromises the kidney and so curtails the removal of wastes from the body. Shock can be due to a number of different mechanisms including not enough blood volume (hypovolemic shock) and not enough output of blood by the heart (cardiogenic shock). The signs and symptoms of shock include low blood pressure (hypotension), overbreathing (hyperventilation), a weak rapid pulse, cold clammy grayish-bluish (cyanotic) skin, decreased urine flow (oliguria), and mental changes (a sense of great anxiety and foreboding, confusion and, sometimes, combativeness).
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Stage: As regards cancer, the extent of a cancer, especially whether the disease has spread from the original site to other parts of the body. See also: Staging.

Stomach: 1. The sac-shaped digestive organ that is located in the upper abdomen, under the ribs. The upper part of the stomach connects to the esophagus, and the lower part leads into the small intestine.
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Strain: 1. An injury to a tendon or muscle resulting from overuse or trauma. 2. A hereditary tendency that originated from a common ancestor. 3. To exert maximum effort. 4. To filter.

Surgery: The word "surgery" has multiple meanings. It is the branch of medicine concerned with diseases and conditions which require or are amenable to operative procedures. Surgery is the work done by a surgeon. By analogy, the work of an editor wielding his pen as a scalpel is s form of surgery. A surgery in England (and some other countries) is a physician's or dentist's office.
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Syndrome: A set of signs and symptoms that tend to occur together and which reflect the presence of a particular disease or an increased chance of developing a particular disease.
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Therapeutic: Relating to therapeutics, that part of medicine concerned specifically with the treatment of disease. The therapeutic dose of a drug is the amount needed to treat a disease.
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Therapy: The treatment of disease.
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Tooth: The structures within the mouth that allow for biting and chewing. Teeth have different shapes, depending on their purpose. The sharp canine and frontal teeth allow for biting, while the flattened, thick molars in the back of the mouth provide grinding surfaces for masticating food. All teeth have essentially the same structure: a hard crown above the gum line, which is attached to two or four roots by a portion called the neck. The roots are covered with a very thin layer of bone, and keep the tooth embedded in the bones of the jaw. The exposed exterior of the tooth is covered with tough enamel. Under the enamel is a thick layer of dentin, and in the center is the pulp. Blood vessels and nerves are found within the pulp.

Trauma: Any injury, whether physically or emotionally inflicted. "Trauma" has both a medical and a psychiatric definition. Medically, "trauma" refers to a serious or critical bodily injury, wound, or shock. This definition is often associated with trauma medicine practiced in emergency rooms and represents a popular view of the term. In psychiatry, "trauma" has assumed a different meaning and refers to an experience that is emotionally painful, distressful, or shocking, which often results in lasting mental and physical effects.
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Ulcerative colitis: A relatively common disease that causes inflammation of the large intestine (the colon). The cause is unknown.
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Urinary: Having to do with the kidneys, ureters, and bladder. The urinary system represents the functional and anatomic aspects of the kidneys, ureters, and bladder.

Urinary tract: The organs of the body that produce and discharge urine. These include the kidneys, ureters, bladder, and urethra.

Urine: Liquid waste. The urine is a clear, transparent fluid. It normally has an amber color. The average amount of urine excreted in 24 hours is from 40 to 60 ounces (about 1,200 cubic centimeters). Chemically, the urine is mainly an aqueous (watery) solution of salt (sodium chloride) and substances called urea and uric acid. Normally, it contains about 960 parts of water to 40 parts of solid matter. Abnormally, it may contain sugar (in diabetes), albumen (a protein) (as in some forms of kidney disease), bile pigments (as in jaundice), or abnormal quantities of one or another of its normal components.

Viruses: Small living particles that can infect cells and change how the cells function. Infection with a virus can cause a person to develop symptoms. The disease and symptoms that are caused depend on the type of virus and the type of cells that are infected.

Vital: Necessary to maintain life. Breathing is a vital function.

World Health Organization: An agency of the United Nations established in 1948 to further international cooperation in improving health conditions. Although the World Health Organization inherited specific tasks relating to epidemic control, quarantine measures, and drug standardization from the Health Organization of the League of Nations (that was set up in 1923) and from the International Office of Public Health at Paris (established in 1909), the World Health Organization was given a broad mandate under its constitution to promote the attainment of "the highest possible level of health" by all people. WHO defines health positively as "a state of complete physical, mental, and social well-being and not merely the absence of disease or infirmity."
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Yogurt: A common dish made of milk curdled and fermented with a culture of Lactobacillus (the milk bacillus). The word was acquired in the 1620s from Turkey. It can be spelled myriad ways including yogurt, yoghurt, yaghourt, yooghurt, yughard, and yaourt. The most popular spellings in the Anglo-Saxon world are yogurt and yoghurt while in France one eats yaourt.