probenecid - oral (cont.)
PRECAUTIONS: Before taking probenecid, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: low blood counts (e.g., aplastic anemia, bone marrow depression), certain type of kidney stone (uric acid).Before using this medication, tell your doctor or pharmacist your medical history, especially of: cancer treatment, a certain enzyme deficiency (G6PD), kidney problems (e.g., kidney stones, obstruction), peptic ulcer disease.This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.Before having surgery, tell your doctor or dentist that you are using this medication.Kidney function declines as you grow older. This medication is removed by the kidneys. Therefore, elderly people may be at greater risk for side effects while using this drug, including stomach problems.During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding.
DRUG INTERACTIONS: Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.This drug should not be used with the following medications because a very serious interaction may occur: cancer chemotherapy, ketorolac.If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting probenecid.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: dyphylline, methotrexate, NSAIDs (e.g., ibuprofen, indomethacin, naproxen), pyrazinamide, salicylates (e.g., high-dose aspirin), certain "water pills" (e.g., furosemide, thiazide diuretics), zidovudine, certain drugs removed from your body by the kidneys (e.g., dapsone, doripenem, ganciclovir, heparin, certain antibiotics such as cephalosporins/penicillins/beta lactams/nitrofurantoin).Aspirin and other salicylate-type medicines can prevent probenecid from being fully effective. Many nonprescription products contain aspirin. Consult your pharmacist before using nonprescription medicines if you are uncertain whether they contain aspirin. Low-dose aspirin should be continued if prescribed by your doctor for specific medical reasons such as heart attack or stroke prevention (usually at dosages of 81-325 milligrams per day). Ask your doctor or pharmacist for more details.Alcohol can decrease this drug's effectiveness. Limit alcohol while taking this medication.This medication may interfere with certain laboratory tests (including urine glucose tests), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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