- What is primidone-oral, and how does it work (mechanism of action)?
- What brand names are available for primidone-oral?
- Is primidone-oral available as a generic drug?
- Do I need a prescription for primidone-oral?
- What are the uses for primidone-oral?
- What are the side effects of primidone-oral?
- What is the dosage for primidone-oral?
- Which drugs or supplements interact with primidone-oral?
- Is primidone-oral safe to take if I'm pregnant or breastfeeding?
- What else should I know about primidone-oral?
What is primidone-oral, and how does it work (mechanism of action)?
Primidone is an oral anticonvulsant (anti-seizure) medication used for treating several types of seizures. Its exact mechanism of action is not known. Primidone is converted into phenobarbital and phenylethylmalonamide (PEMA) in the body. Primidone, phenobarbital, and PEMA all have anticonvulsant activity. In addition to its anticonvulsant activity, PEMA increases the anticonvulsant activity of phenobarbital. The FDA approved primidone in March, 1954.
What brand names are available for primidone-oral?
Is primidone-oral available as a generic drug?
GENERIC AVAILABLE: Yes
Do I need a prescription for primidone-oral?
What are the uses for primidone-oral?
Primidone is used alone or with other medications for treating grand mal, psychomotor, or focal epileptic seizures. It may be effective for grand mal seizures that are not responsive to other anticonvulsants. Primidone should not be used by patients with porphyria and people who are allergic to phenobarbital.
What are the side effects of primidone-oral?
Common side effects of primidone include:
- Difficulty speaking (dysarthria)
- Burning, tingling from damaged nerves (paresthesia)
- Difficulty moving (ataxia)
- Loss of balance (vertigo)
- Paradoxical excitement (children)
- Hyperactivity (children)
Possible serious side effects of primidone include:
- Acute psychosis
- Folate-deficiency anemia
- Liver toxicity
- Low blood calcium
- Weakening of bones
- Serious skin reactions (for example, Stevens-Johnson syndrome)
Seizure medications increase the risk of suicidal thoughts or behavior. Patients treated with seizure medications should be observed for the emergence or worsening of depression, suicidal thoughts or behavior, and unusual changes in mood or behavior.
Suddenly stopping medications for seizures may cause seizures.
Quick GuideEpilepsy: Symptoms, Causes and Treatment
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