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The Cleveland Clinic

Premature Menopause

In the U.S., the average age of onset for "natural" menopause is 51. However, because of genetics, illness, or medical procedures, some women go through menopause before the age of 40. Menopause that occurs before this age, whether natural or induced, is known as "premature" menopause.

In addition to dealing with hot flashes, mood swings and other symptoms that accompany menopause, many women undergoing premature menopause have to cope with additional physical and emotional concerns. For example, since menopause signals the end of a woman's fertile years, a woman who wishes to get pregnant is likely to have trouble.

What Are the Symptoms of Premature Menopause?

Symptoms of premature menopause are often the same as those experienced by women undergoing natural menopause and may include:

  • Irregular or missed periods
  • Periods that are heavier or lighter than usual
  • Hot flashes (a sudden feeling of warmth that spreads over the upper body)

These symptoms are a sign that the ovaries are producing less estrogen.

Along with the above symptoms, some women may experience:

In addition to the symptoms listed above, if you are under the age of 40 and experience any of the following conditions, you should see your doctor to determine whether you are undergoing premature menopause:

  • You have undergone chemotherapy or radiation.
  • You or a family member has an autoimmune disorder such as hypothyroidism, Graves' disease or lupus.
  • You have unsuccessfully tried to become pregnant for more than a year.
  • Your mother or sister experienced premature menopause.


Next: How is premature menopause diagnosed? »

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What is a depressive disorder?

Depressive disorders have been with mankind since the beginning of recorded history. In the Bible, King David, as well as Job, suffered from this affliction. Hippocrates referred to depression as melancholia, which literally means black bile. Black bile, along with blood, phlegm, and yellow bile were the four humors (fluids) that described the basic medical physiology theory of that time. Depression, also referred to as clinical depression, has been portrayed in literature and the arts for hundreds of years, but what do we mean today when we refer to a depressive disorder? In the 19th century, depression was seen as an inherited weakness of temperament. In the first half of the 20th century, Freud linked the development of depression to guilt and conflict. John Cheever, the author and a modern sufferer of depressive disorder, wrote of conflict and experiences with his parents as influencing his development of depression.

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