GENERIC NAME: pregabalin
BRAND NAME: Lyrica
GENERIC AVAILABLE: No
USES: Pregabalin is used for neuropathic pain associated with diabetic peripheral neuropathy or postherpetic neuralgia, spinal cord injury, and in combination with other drugs to treat partial onset seizures in adults. It also is used for treating fibromyalgia.
WARNING: Antiepileptic medications have been associated with increased risk of suicidal thinking and behavior. Anyone considering the use of antiepileptic drugs must balance this risk of suicide with the clinical need. Patients who are started on therapy should be closely observed for clinical worsening, suicidal thoughts, or unusual changes in behavior.
SIDE EFFECTS: The most common side effects of pregabalin are
- dry mouth,
- edema (accumulation of fluid),
- blurred vision,
- double vision (diplopia),
- weight gain,
- fatigue (tiredness),
- tremor and
- difficulty concentrating.
Other side effects include
- increased appetite,
- reduced blood platelet counts, and
- increased blood creatinine kinase levels.
Increased creatinine kinase can be a sign of muscle injury, and in clinical trials three patients experienced rhabdomyolysis (severe muscle injury). Therefore, patients should report unexplained muscle pain, tenderness or weakness to their doctors, especially if associated with fever and malaise (reduced well-being). Pregabalin has rarely been associated with angioedema (swelling of the face, tongue, lips, and gums, throat and larynx).
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