pregabalin, Lyrica

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

Fibromyalgia Overview Slideshow

GENERIC NAME: pregabalin

BRAND NAME: Lyrica

PRESCRIPTION: Yes

GENERIC AVAILABLE: No

USES: Pregabalin is used for neuropathic pain associated with diabetic peripheral neuropathy or postherpetic neuralgia, spinal cord injury, and in combination with other drugs to treat partial onset seizures in adults. It also is used for treating fibromyalgia.

WARNING: Antiepileptic medications have been associated with increased risk of suicidal thinking and behavior. Anyone considering the use of antiepileptic drugs must balance this risk of suicide with the clinical need. Patients who are started on therapy should be closely observed for clinical worsening, suicidal thoughts, or unusual changes in behavior.

SIDE EFFECTS: The most common side effects of pregabalin are

Other side effects include

Increased creatinine kinase can be a sign of muscle injury, and in clinical trials three patients experienced rhabdomyolysis (severe muscle injury). Therefore, patients should report unexplained muscle pain, tenderness or weakness to their doctors, especially if associated with fever and malaise (reduced well-being). Pregabalin has rarely been associated with angioedema (swelling of the face, tongue, lips, and gums, throat and larynx).

Medically Reviewed by a Doctor on 3/31/2016

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