GENERIC NAME: prednisolone (oral)
BRAND NAMES: Flo-Pred, Pediapred, Orapred, Orapred ODT
DRUG CLASS AND MECHANISM: Prednisolone is a synthetic adrenal corticosteroid (cortisone). Corticosteroids are natural substances produced by the adrenal glands located adjacent to the kidneys. Corticosteroids have potent anti-inflammatory properties, and are used in a wide variety of inflammatory conditions such as arthritis, colitis, asthma, bronchitis, certain skin rashes, and allergic or inflammatory conditions of the nose and eyes. There are numerous preparations of corticosteroids including tablets, capsules, liquids, topical creams and gels, inhalers, eye drops, as well as injectable and intravenous solutions. The FDA approved prednisolone in June 1955.
PRESCRIBED FOR: Prednisolone is used to achieve prompt suppression of inflammation from inflammatory and allergic conditions.
- Examples of inflammatory conditions include rheumatoid arthritis, systemic lupus, acute gouty arthritis, psoriatic arthritis, ulcerative colitis, and Crohn's disease.
- Severe allergic conditions that fail conventional treatment may also respond to prednisolone. Examples include bronchial asthma, allergic rhinitis (hay fever), drug-induced dermatitis, and contact and atopic dermatitis.
- Chronic skin conditions treated with prednisolone include dermatitis herpetiformis, pemphigus, severe psoriasis and severe seborrheic dermatitis.
- Chronic allergic and inflammatory conditions of the uvea, iris, conjunctiva, and optic nerves of the eyes are also treated with prednisolone.
- Prednisolone also is used in the treatment of
- blood cell cancers (leukemias), and lymph gland cancers (lymphomas),
- blood diseases involving destruction of platelets by the body's own immune cells (idiopathic thrombocytopenia purpura), and destruction of red blood cells by immune cells (autoimmune hemolytic anemia),
- thyroiditis, and
- Prednisolone also is used as a hormone replacement in patients whose adrenal glands are unable to produce sufficient amounts of corticosteroids.
Quick GuidePsoriasis Types, Images, Treatments
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Need help identifying pills and medications?
Use the pill identifier tool on RxList.