prazosin (Minipress)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

Other side effects reported in post-marketing trials include:

PRESCRIPTION: Yes

GENERIC AVAILABLE: Yes

PREPARATIONS: Oral capsules: 1, 2, and 5 mg.

STORAGE: Capsules should be stored at room temperature, between 59 F and 86 F (15 C and 30 C).

DOSING:

  • The dose of prazosin should be adjusted based on the individual patient response.
  • For the treatment of high blood pressure: Most patients are started with 1 mg by mouth 2-3 times a day. To decrease the risk of orthostatic hypotension the first dose may be given at bedtime. Orthostatic hypotension is a drop in blood pressure when standing up from a sitting or lying position. Dosage may be increased gradually over time to a total daily dose of 20 mg given in multiple doses.
  • If adding another blood pressure lowering agent or water pill (diuretic) to prazosin therapy, the dose of prazosin should be reduced to 1-2 mg by mouth three times a day, followed by slow increases in dose as needed.
  • As elderly patients are more sensitive to the side effects of low blood pressure, dose reduction in the elderly is necessary. Most elderly patients are started on 1 mg by mouth 1-2 times daily.
  • The safety and effectiveness of prazosin in children has not been established.
Medically Reviewed by a Doctor on 6/1/2015

Quick GuideHow to Lower Blood Pressure: Exercise Tips (Pictures)

How to Lower Blood Pressure: Exercise Tips (Pictures)
FDA Logo

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

RxList Logo

Need help identifying pills and medications?

Use the pill identifier tool on RxList.

Subscribe to MedicineNet's Heart Health Newsletter

By clicking Submit, I agree to the MedicineNet's Terms & Conditions & Privacy Policy and understand that I may opt out of MedicineNet's subscriptions at any time.

Health Solutions From Our Sponsors