pravastatin/buffered aspirin-oral, Pravigard PAC (cont.)

DRUG INTERACTIONS: See also the How to Use section. This drug should not be used with the following medications because very serious interactions may occur: mifepristone. If you are currently using any of these medications, tell your doctor or pharmacist before starting pravastatin/buffered aspirin. Use caution if the following drugs are combined with pravastatin because serious side effects such as muscle injury (myopathy) infrequently could occur: fibrates (e.g., gemfibrozil, fenofibrate), high-dose niacin (1 gram or more per day). Before using these medications, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: acetazolamide, atazanavir, azole antifungals (e.g., itraconazole, ketoconazole), "blood thinners" (e.g., heparin, warfarin), cholestyramine, colestipol, corticosteroids (e.g., prednisone), cyclosporine, delavirdine, gabapentin, ginkgo biloba, levothyroxine, medication for gout or diabetes, methotrexate, NSAIDs (e.g., ibuprofen, naproxen), quinidine, quinolone antibiotics (e.g., ciprofloxacin, levofloxacin), tetracycline antibiotics (e.g., tetracycline, minocycline), ticlopidine, valproic acid. Check the labels on all your medicines because they may contain aspirin or aspirin-like NSAIDs (e.g., ibuprofen, naproxen, ketoprofen). Ask your pharmacist about the safe use of those products. Do not start or stop any medicine without doctor or pharmacist approval.

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