- What is pravastatin, and how does it work (mechanism of action)?
- What brand names are available for pravastatin?
- Is pravastatin available as a generic drug?
- Do I need a prescription for pravastatin?
- What are the side effects of pravastatin?
- What is the dosage for pravastatin?
- Which drugs or supplements interact with pravastatin?
- Is pravastatin safe to take if I'm pregnant or breastfeeding?
- What else should I know about pravastatin?
What is the dosage for pravastatin?
The dose range of pravastatin is 10-80 mg daily. The usual starting dose in adults is 40 mg once daily. The maximum dose is 80 mg per day. The starting dose for patients with major liver or kidney dysfunction is 10 mg daily.
The dose for children (8-13 years old) is 20 mg daily, and the dose for adolescents (14-18 years old) is 40 mg daily.
Which drugs or supplements interact with pravastatin?
Bile acid sequestrants such as cholestyramine (Questran) may reduce the absorption of pravastatin from the intestine and thereby reduce its effects. Therefore, pravastatin should be taken one hour before or four hours after bile acid sequestrants. The use of pravastatin with nicotinic acid, gemfibrozil (Lopid) or other drugs that cause liver or muscle problems may increase the risk of muscle problems.
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.








