pramoxine (Itch-X, PrameGel, Orax, Sarna Sensitive, and Others)

  • Medical Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

Do I need a prescription for pramoxine?

Yes, you need a prescription from your doctor or other health care professional to obtain this medication.

What are the uses for pramoxine?

This medicine is used for the temporary relief of pain and itching associated with:

What are the side effects and adverse effects of pramoxine?

In some patients, pramoxine may act as a "sensitizer," and:

What is the dosage for pramoxine?

  • Apply one dose topically to the affected areas 3 to 4 times per day.
  • This drug is intended only for external use and should not be applied to open cuts or wounds or damaged skin.
  • If the condition does not improve after 7 days of use, a doctor, pharmacist, or other health care professional should be consulted.

Which drugs or supplements interact with this medication?

There are no drug interactions listed for this medication.

What brand names are available for pramoxine?

There are numerous brand names for pramoxine, far too many to list here. Examples include:

  • Itch-X
  • PrameGel
  • Orax
  • Sarna Sensitive

The brand Anti-Itch has been discontinued in the US.

Is this drug safe to use during pregnancy or while breastfeeding?

  • Researchers and doctors don't know if pramoxine is harmful if used during pregnancy.
  • Doctors and researchers don't know if pramoxine is secreted into human milk.
  • Consult with your doctor if you are considering using this topical anti-itch cream.

What else should I know about pramoxine?

This medication is available in formulations of:

  • Topical Cream: 1%
  • Topical Gel: 1%
  • Topical Lotion: 1%
  • Topical Spray: 1%

Keep this medication stored at room temperature, 15 C-30 C (59 F-86 F).

Medically reviewed by John Cunha, DO

Reference: FDA Prescribing Information

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Reviewed on 8/8/2017
References
Medically reviewed by John Cunha, DO

Reference: FDA Prescribing Information

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