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- What is pramlintide, and how does it work (mechanism of action)?
- What brand names are available for pramlintide?
- Is pramlintide available as a generic drug?
- Do I need a prescription for pramlintide?
- What are the side effects of pramlintide?
- What is the dosage for pramlintide?
- Which drugs or supplements interact with pramlintide?
- Is pramlintide safe to take if I'm pregnant or breastfeeding?
- What else should I know about pramlintide?
What is pramlintide, and how does it work (mechanism of action)?
Pramlintide is an injectable drug that lowers the level of sugar (glucose) in blood. It is used for treating type 1 and type 2 diabetes. Pramlintide is a synthetic (man-made) hormone that resembles human amylin. Amylin is a hormone that is produced by the pancreas and released into the blood after meals where it helps the body to regulate levels of blood glucose. Amylin acts in several ways to control blood glucose. It slows the rate at which food (including glucose) is absorbed from the intestine. Amylin reduces the production of glucose by the liver by inhibiting the action of glucagon, a hormone produced by the pancreas that stimulates the production of glucose by the liver. Amylin also reduces appetite. In studies, pramlintide-treated patients achieved lower blood glucose levels and experienced weight loss. Pramlintide was approved by the FDA in March 2005.
What brand names are available for pramlintide?
Is pramlintide available as a generic drug?
GENERIC AVAILABLE: No.
Do I need a prescription for pramlintide?
What are the side effects of pramlintide?
Common side effects of pramlintide include:
- hypoglycemia (excessively low blood glucose),
- abdominal pain,
- weight loss, and
Nausea decreases with continued administration of pramlintide and is less severe when pramlintide is slowly increased to the desired dose. When used with insulin, especially in patients with type 1 diabetes, severe hypoglycemia may occur. If severe hypoglycemia occurs, it usually manifests within 3 hours after receiving pramlintide.
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