potassium citrate (Urocit-K) (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

PRESCRIPTION: Yes

GENERIC AVAILABLE: Yes

PREPARATIONS: Potassium citrate is available in extended-release tablets. They are available in 5 mEq (540 mg), 10 mEq (1080 mg), and 15 mEq (1620 mg) strengths. The packets for oral solution were discontinued in the U.S.

STORAGE: Store potassium citrate tablets at room temperature in a tightly closed container.

DRUG INTERACTIONS: Potassium citrate should be used with caution with potassium-sparring diuretics, which can increase potassium levels in body and potentially lead to cardiac arrest.

Drugs that slow transit of food through the intestine may delay passage of potassium tablets through the digestive system and result in increased irritation, ulceration or narrowing of the small intestine. Examples of such drugs include atropine, loperamide (Imodium), liraglutide (Saxzenda, Victoza) and similar drugs.

Angiotensin converting enzyme (ACE) inhibitors (for example, enalapril [Vasotec]), angiotensin receptor blockers (ARB) drugs (for example, valsartan [Diovan]) and certain diuretics (for example, spironolactone [Aldactone] and triamterene [Dyrenium]) increase potassium levels, causing high potassium levels in the blood when combined with potassium supplements. Potassium blood levels should be measured regularly in these patients.

Salt substitutes (for example, Mrs. Dash) often contain potassium. Therefore, patients using salt substitutes while taking potassium supplements may develop high levels of potassium in the blood.

PREGNANCY: There are no adequate studies done on potassium citrate to determine safe and effective use in pregnant women.

NURSING MOTHERS: Normally, potassium ions are present in breast milk. It is not known whether administering potassium citrate can further increase potassium levels. Therefore, potassium citrate should only be given if needed.

Medically reviewed by Omudhome Ogbru, PharmD

REFERENCES:

Urocit-K Prescribing Information.

MedscapeReference. Urocit-K.


Medically Reviewed by a Doctor on 4/14/2015


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