potassium citrate (Urocit-K) (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

Drugs that slow transit of food through the intestine (for example, atropine and loperamide [Imodium]) may delay passage of potassium tablets through the digestive system and result in increased irritation, ulceration or narrowing of the small intestine.

Angiotensin converting enzyme (ACE) inhibitors (for example, enalapril [Vasotec]), angiotensin receptor blockers (ARB) drugs (for example, valsartan [Diovan]) and certain diuretics (for example, spironolactone [Aldactone] and triamterene [Dyrenium]) increase potassium levels, causing high potassium levels in the blood when combined with potassium supplements. Potassium blood levels should be measured regularly in these patients.

Salt substitutes (for example, Mrs. Dash) often contain potassium. Therefore, patients using salt substitutes while taking potassium supplements may develop high levels of potassium in the blood.

PREGNANCY: There are no adequate studies done on potassium citrate to determine safe and effective use in pregnant women.

NURSING MOTHERS: Normally, potassium ions are present in breast milk. It is not known whether administering potassium citrate can further increase potassium levels. Therefore, potassium citrate should only be given if needed.

SIDE EFFECTS: Side effects of potassium citrate are abdominal discomfort, nausea, vomiting, diarrhea, increased potassium levels, and rarely cardiac arrest. Potassium supplements can cause bleeding or perforation of the stomach or small intestine from ulcers, and narrowing (stricture) of the small intestine from healed ulcers.

REFERENCES:

Urocit-K Prescribing Information.

MedscapeReference. Urocit-K.


Medically Reviewed by a Doctor on 5/27/2014


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