Post-Polio Syndrome (cont.)
What research is being conducted on post-polio syndrome?
Scientists are working on a variety of investigations
that may one day help individuals with post-polio syndrome. Some basic researchers are studying
the behavior of motor neurons many years after a polio attack. Others are
looking at the mechanisms of fatigue and are trying to discover the role played
by the brain, spinal cord,
peripheral nerves, the neuromuscular junction (the site where a nerve cell meets
the muscle cell it helps activate), and the muscles.
Determining if there is an immunological link in post-polio syndrome is also an area of
intense interest. Researchers who discovered inflammation around motor neurons
or muscles are trying to find out if this is due to an immunological response.
Other investigators have discovered that fragments of the poliovirus, or
mutated versions of it, are in the spinal fluid of some survivors. The
significance of this finding is not known and more research is being done.
Where can I get more information?
For more information on neurological disorders or research programs funded by
the National Institute of Neurological Disorders and Stroke, contact the
Institute's Brain Resources and Information Network (BRAIN) at:
BRAIN
P.O. Box 5801
Bethesda, MD 20824
(800) 352-9424
http://www.ninds.nih.gov
Information also is available from the following organizations:
Post-Polio Health International/
4207 Lindell Blvd.
#110
St. Louis, MO 63108-2930
info@post-polio.org
http://www.post-polio.org
Tel: 314-534-0475
Fax: 314-534-5070
March of Dimes Foundation
1275 Mamaroneck Avenue
White Plains, NY 10605
askus@marchofdimes.com
http://www.marchofdimes.com
Tel: 914-428-7100 888-MODIMES (663-4637)
Fax: 914-428-8203
SOURCE: National Institute of Neurological Disorders and Stroke, National Institutes of Health
Last Editorial Review: 10/29/2008
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