MedicineNet.com

About Us | Privacy Policy | Site Map
February 8, 2012
The Cleveland Clinic


What Is Portal Hypertension?

Introduction to Portal Hypertension

Portal hypertension is an increase in the blood pressure within a system of veins called the portal venous system. Normally, the veins come from the stomach, intestine, spleen, and pancreas, merge into the portal vein, which then branches into smaller vessels and travels through the liver. If the vessels in the liver are blocked, it is hard for the blood to flow causing high pressure in the portal system.

When the pressure becomes too high, the blood backs up and finds other ways to flow back to the heart, where it is pumped to the lungs, where it gets rid of waste products and picks up oxygen. The blood can travel to the veins in the esophagus (esophageal varices), in the skin of the abdomen, and the veins of the rectum and anus (hemorrhoids) to get around the blockages in the liver.

What Causes Portal Hypertension?

The most common cause of portal hypertension is cirrhosis of the liver. Cirrhosis results from scarring of a liver injury caused by hepatitis, alcohol abuse, or other causes of liver damage. In cirrhosis, scar tissue blocks the flow of blood through the liver.

Other causes of portal hypertension include blood clots in the portal vein, blockages of the veins that carry the blood from the liver to the heart, and a parasitic infection called schistosomiasis. Sometimes the cause is unknown.

What Are the Symptoms of Portal Hypertension?

The onset of portal hypertension may not always be associated with specific symptoms that identify what is happening in the liver. But if you have liver disease that leads to cirrhosis, the chance of developing portal hypertension is high.

The main symptoms and complications of portal hypertension include:

  • Gastrointestinal bleeding: Black, tarry stools or blood in the stools; or vomiting of blood due to the spontaneous rupture and hemorrhage from varices.
  • Ascites (an accumulation of fluid in the abdomen).
  • Encephalopathy or confusion and forgetfulness caused by poor liver function.
  • Reduced levels of platelets, blood cells that help form blood clots, or white blood cells, the cells that fight infection.



MedicineNet Doctors

Suggested Reading on Portal Hypertension by Our Doctors

  • Related Diseases & Conditions

    • Hemorrhoids
      • Hemorrhoid is an enlarged vein in the walls of the anus and sometimes around the rectum, usually caused by untreated constipation, but occasionally associated with chronic diarrhea. If untreated, hemorrhoids can worsen, protruding from the anus. Also known as piles.
    • Cirrhosis (Liver)
      • Cirrhosis of the liver refers to a disease in which normal liver cells are replaced by scar tissue caused by alcohol and viral hepatitis B and C. This disease leads to abnormalities in the liver's ability to handle toxins and blood flow, causing internal bleeding, kidney failure, mental confusion, coma, body fluid accumulation, and frequent infections. Symptoms include yellowing of the skin, itching, and fatigue.
    • Liver Disease
      • Liver disease can be cause by a variety of things including infection (hepatitis), diseases such as gallstones, high cholesterol or triglycerides, blood flow obstruction to the liver, and toxins (medications and chemicals). Symptoms of liver disease depends upon the cause; however, common symptoms may include nausea, vomiting, upper right abdominal pain, and jaundice. Treatment depends upon the cause of the liver disease.
    • Alcoholism
      • Alcoholism is a disease that includes alcohol craving and continued drinking despite repeated alcohol-related problems, such as losing a job or getting into trouble with the law.
    • Ascites
      • Ascites, the accumulation of fluid in the abdominal cavity is most commonly caused by cirrhosis of the liver. Some of the other causes of ascites include portal hypertension, congestive heart failure, blood clots, and pancreatitis. The most common symptoms include increased abdominal girth and size, abdominal bloating, and abdominal pain. Treatment depends on the cause of ascites.
    • The Digestive System
      • Digestion is the complex process of turning food you eat into the energy you need to survive. The digestive process also involves creating waste to be eliminated, and is made of a series of muscles that coordinate the movement of food.
    • Bleeding Varices
    • Choledochal Cysts
      • Choledochal cysts are cysts of the bile ducts. There are several different types of choledochal cysts. These cysts are congenital, however, their cause is not known. Symptoms of choledochal cysts in infants include an enlarged liver and jaundice. In older people, the cysts cause abdominal pain, jaundice, cholangitis, gallstones, and pancreatitis. Treatment for choledochal cysts is surgery.
  • Medications

  • Procedures & Tests

  • Pictures, Images & Illustrations

  • Doctor's & Expert's Views

  • Health News

  • Health Features

Hypertension

Get tips on handling your hypertension.



Symptom Checker: Your Guide to Symptoms & Signs: Pinpoint Your Pain



Portal Hypertension

What is liver disease?

Liver disease is any disturbance of liver function that causes illness. The liver is responsible for many critical functions within the body and should it become diseased or injured, the loss of those functions can cause significant damage to the body. Liver disease is also referred to as hepatic disease.

Liver disease is a broad term that covers all the potential problems that may occur to cause the liver to fail to perform its designated functions. Usually, more than 75% or three quarters of liver tissue needs to be affected before decrease in function occurs.

The liver the largest solid organ in the body; and is also considered a gland because among its many functions, it makes and secretes bile. The liver is located in the upper right portion of the abdomen protected by the rib cage. It has two main lobes that are made up of tiny lobules. The liver cells have two different sources of blood supply. The hepatic ...

Read the Liver Disease article »







Use Pill Finder Find it Now

Pill Identifier on RxList

  • quick,
    easy,
    pill identification

Find a Local Pharmacy

  • including
    24 hour
    pharmacies