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SIDE EFFECTS: See also Warning section.Pain, redness, and swelling at the injection site may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these rare but very serious side effects occur: slow/shallow breathing, facial flushing, dizziness, unexplained fever, muscle weakness, severe headache, stiff neck, seizures, vision changes, change in the amount of urine, red/pink urine.Use of this medication for prolonged or repeated periods may result in a new bacterial or fungal infection (opportunistic infection). Tell your doctor if you notice any symptoms of a new infection (e.g., white patches in your mouth, a change in vaginal discharge).A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

PRECAUTIONS: Before using polymyxin B, tell your doctor or pharmacist if you are allergic to it; or to similar drugs such as colistin; or if you have any other allergies.Before using this medication, tell your doctor or pharmacist your medical history, especially of: disease of the nerves/muscles (e.g., myasthenia gravis), kidney disease.Before having surgery, tell your doctor or dentist that you are using this medication.During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.It is not known if this drug passes into breast milk. Consult your doctor before breast-feeding.

Report Problems to the Food and Drug Administration   You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088. Need help identifying pills and medications? Use the pill identifier tool on RxList.