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polymyxin b sulfate-injectable (cont.)

PRECAUTIONS: Tell your doctor your medical history, especially of: neuromuscular disease (e.g., myasthenia gravis), kidney disease, any allergies (especially to polymyxin antibiotics such as colistin). Tell your doctor if you are pregnant before using this medication. It is not known if this drug passes into breast milk. Consult your doctor before breast-feeding.

DRUG INTERACTIONS: Tell your doctor of all prescription and nonprescription drugs you may use, especially: aminoglycoside antibiotics (e.g., gentamicin, tobramycin, paromomycin), anesthesia drugs or muscle relaxants (e.g., tubocurarine, succinylcholine, gallamine, decamethonium), sodium citrate, quinine/quinidine, colistin, bacitracin. Do not start or stop any medicine without doctor or pharmacist approval.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include: seizures, bloody or pink-colored urine, change in amount of urine, tingling or numbness of the hands/feet.

NOTES: Do not share this medication with others. Laboratory and/or medical tests may be performed to monitor for side effects and response to treatment.

MISSED DOSE: If you miss a dose or your dose is interrupted, contact your doctor or pharmacist promptly to establish a new dosing schedule.

STORAGE: Store vials at room temperature between 59 and 86 degrees F (15 to 30 degrees C) away from moisture. Protect vials from light. Retain in carton until time of use. After mixing and dilution in correct fluids (consult your pharmacist for details), the drug is stable at refrigerator temperature for 72 hours. Discard any unused liquid.


Last Editorial Review: 3/2/2005




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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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