Polyarteritis Nodosa (cont.)
How is polyarteritis treated?
Polyarteritis is a serious illness that can be fatal.
Treatment is directed toward decreasing the inflammation of the arteries by
suppressing the immune system. Medications used to treat polyarteritis
nodosa include high-dose intravenous and oral cortisone medications such as
prednisone, as well as immunosuppressive drugs such as cyclophosphamide (Cytoxan) or azathioprine (Imuran).
When hepatitis B is present in patients with polyarteritis, antiviral medications (such as vidarabine and interferon-alpha) are used as primary treatments. Some studies have used various combinations of antiviral medications, plasma exchange, and immunosuppressive drugs.
- Polyarteritis nodosa is an autoimmune disease that affects
arteries.
- Common areas affected include the muscles, joints,
intestines (bowels), nerves, kidneys, and skin.
- Diagnosis of polyarteritis nodosa is confirmed by a biopsy
of involved tissue or angiography.
- Treatment is directed toward decreasing the inflammation of
the arteries.
References:
Clinical Primer of Rheumatology, Lippincott Williams & Wilkens, edited by William Koopman, et al., 2003.
Kelley's Textbook of Rheumatology, W B Saunders Co, edited by Shaun Ruddy, et al., 2004.
Last Editorial Review: 9/11/2007
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